Eisenmenger's syndrome

From Dog

Eisenmenger's syndrome specifically refers to the combination of systemic-to-pulmonary communication, pulmonary vascular disease, and cyanosis.

In dogs, this condition is often associated with Tetralogy of Fallot and has been reported in the Border Collie[1].

Clinically affected dogs are usually young and present with respiratory distress, cyanosis, exercise intolerance and syncope.

Blood tests usually reveal secondary erythrocytosis.

Treatment with sildenafil may help alleviate secondary pulmonary hypertension[2].


  1. Lieb A et al (1998) Case report: Eisenmenger syndrome in a 9-month-old border collie puppy. Schweiz Arch Tierheilkd 140(4):164-167
  2. Nakamura K et al (2011) Effects of sildenafil citrate on five dogs with Eisenmenger's syndrome. J Small Anim Pract 52(11):595-598