Enoxaparin
From Dog
Enoxaparin binds to and accelerates the activity of antithrombin III. By activating antithrombin III, enoxaparin preferentially potentiates the inhibition of coagulation factors Xa and IIa[1].
This drug is used in dogs to prevent thromboembolism associated with DIC and heartworm disease.
Recommended dose in dogs is 100 U/kg given subcutaneously as a single injection[2].
References
- ↑ Stassen JM et al (1993) Comparative effects of enoxaparin and heparin on arterial and venous clot lysis with alteplase in dogs. Thromb Haemost 69(5):454-459
- ↑ Yoon WK et al (2011) Catheter-guided percutaneous heartworm removal using a nitinol basket in dogs with caval syndrome. J Vet Sci 12(2):199-201
