Ependymomas originate from the epithelium lining the ventricles and central canal of the spinal cord. They are rare, but have been reported most frequently in the German Shepherd and brachycephalic breeds, particularly the Boxer, Beagle and Maltese.
Mestastases within the CSF system may be observed. Ependymomas of the fourth ventricle may encircle the brain stem. Both epithelial and fibrillary varieties have been described.
Types of ependymomas include:
Affected dogs often present with neurological disease such as circling, seizures, proprioceptive deficits, depression, weight loss and anorexia. Clinical signs are usually sudden-onset, with signs occurring within a few weeks, but some cases may be protracted over 2 - 3 months.
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