Everglades virus is an alphavirus included in the Venezuelan equine encephalitis virus (VEEV) complex.
In humans, this virus causes febrile disease, sometimes accompanied by neurologic manifestations.
Field studies in VEEV-enzootic foci outside Florida also indicate that dogs are frequently infected during outbreaks. Domestic dogs tested after epidemics in Colombia, Venezuela, and Guatemala commonly had neutralizing antibody to VEEV
Clinical signs are usually absent but dogs presenting with arboviral symptoms, particularly fever, myalgia, joint stiffness, etc, must be considered as possible candidates for everglades viral infection.
Antibody titers in dogs naturally wane to low levels after a 1- to 2-year period.
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