From Dog

Fludrocortisone acetate (Florinef) is an oral long-acting moderate glucocorticoid and potent mineralocorticoid used in canine medicine for treatment of hypoadrenocorticism.

In use with hypoadrenocorticism, this drug is given as a twice daily medication[1].

The daily dose of fludrocortisone required in hypoadrenocorticism usually increases significantly over a number of years, starting at maintenance doses of 10 - 15 μg/kg and increasing as required to 22.6 μg/kg[2].


  1. Richartz J & Neiger R (2011) Hypoadrenocorticism without classic electrolyte abnormalities in seven dogs. Tierarztl Prax Ausg K Kleintiere Heimtiere 39(3):163-169
  2. Melián C & Peterson ME (1996) Diagnosis and treatment of naturally occurring hypoadrenocorticism in 42 dogs. J Small Anim Pract 37(6):268-275