Gonadal dysgenesis syndrome (Xo syndrome, Turner syndrome) is a rare dvelopmental abnormality of dogs characterized by chromosomal abnormalities and quiescent ovarian function.
In the few reported cases, affected bitches had abnormal oestrus cycle and apparently persistent follicles.
No other phenotypic abnormalities were reported, unlike human patients which show a number of physical changes with this condition.
Karyotyping usually reveals XX-XO mosaicism (some chromosomes are entirely missing the additional X chromosome).
- Smith FW et al (1989) X-chromosomal monosomy (77,X0) in a Doberman Pinscher with gonadal dysgenesis. J Vet Intern Med 3(2):90-95
- Mayenco-Aguirre AM et al (1999) Canine gonadal dysgenesis syndrome: a case of mosaicism (77,XO-78,XX). Vet Rec 145(20):582-584