From Dog

Hydrochlorothiazide is a calcium-sparing thiazide diuretic drug.

This drug is available as an oral medication which is well absorbed throughout the small intestine[1].

Hydrochlorothiazide is primarily used for:

Recommended dose rate in dogs is 2 mg/kg orally twice daily.


  1. Ritschel WA et al (1991) In vitro/in vivo evaluation of hydrochlorothiazide in experimental hydrochlorothiazide/triamterene combination tablets in beagle dogs. Arzneimittelforschung 41(3):208-211
  2. Lulich JP et al (2001) Effects of hydrochlorothiazide and diet in dogs with calcium oxalate urolithiasis. J Am Vet Med Assoc 218(10):1583-1586
  3. Huang XH et al (2005) Pharmacokinetic and pharmacodynamic interaction between irbesartan and hydrochlorothiazide in renal hypertensive dogs. J Cardiovasc Pharmacol 46(6):863-869