Hyperlipidemia

From Dog

Familial hyperlipidemia is a genetic disease of a number of dog breeds.

Hyperlipidemia is defined as an elevation in serum triglycerides and/or cholesterol.

It has been reported in:

A predisposition to pancreatitis, corneal lipid dystrophy, cataract formation and cutaneous xanthoma[3] is common.

Affected dogs often show elevated levels of circulating insulin (> 12.5 mU/L), correlating with insulin resistance[4].

Management of this condition would require use of low fat diets and statins to attempt to reduce circulatory lipidemia.

References

  1. Manning PJ (1979) Thyroid gland and arterial lesions of Beagles with familial hypothyroidism and hyperlipoproteinemia. Am J Vet Res 40(6):820-828
  2. Xenoulis PG et al (2011) Serum triglyceride concentrations in Miniature Schnauzers with and without a history of probable pancreatitis. J Vet Intern Med 25(1):20-25
  3. Banajee KH et al (2011) Idiopathic solitary cutaneous xanthoma in a dog. Vet Clin Pathol 40(1):95-98
  4. Xenoulis PG et al (2011) Association of hypertriglyceridemia with insulin resistance in healthy Miniature Schnauzers. J Am Vet Med Assoc 238(8):1011-1016