Imidocarb dipropionate

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Imidocarb diproprionate is a urea byproduct used primarily for treatment of canine Babesia canis infections.

This drug can be given solely[1] or in a cocktail mixture with clindamycin, diminazene[2] or toltrazuril.

Results are usually good, but this drug does not appear effective against Babesia gibsoni or other protozoa such as Hepatozoon spp[3], where pentamidine isethionate may be more effective.

Recommended dose rate is 5.0 - 6.6 mg/kg given subcutaneously or intramuscularly at an interval of 2 to 3 weeks.

References

  1. Allison RW et al (2011) Babesia canis rossi infection in a Texas dog. Vet Clin Pathol 40(3):345-50
  2. Lin EC et al (2012) The therapeutic efficacy of two antibabesial strategies against Babesia gibsoni. Vet Parasitol 186(3-4):159-164
  3. Pasa S et al (2011) Failure of combination therapy with imidocarb dipropionate and toltrazuril to clear Hepatozoon canis infection in dogs. Parasitol Res 109(3):919-926