Lansoprazole

From Dog

Lansoprazole is a proton-pump inhibitor similar to omeprazole which has both antiemetic and gastric acid reduction properties[1].

This drug is primarily used for dogs with chronic vomiting associated with gastritis or Helicobacter spp infections[2] as well as gastrinoma.

It has also been used as a rescue protocol in dogs undergoing chemotherapy with adverse side-effects associated with treatment[3].

Recommended dose rate is 5 mg/Kg once daily.

References

  1. Hori Y et al (2011) A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals. J Pharmacol Exp Ther 337(3):797-804
  2. Anacleto TP et al (2011) Studies of distribution and recurrence of Helicobacter spp. gastric mucosa of dogs after triple therapy. Acta Cir Bras 26(2):82-87
  3. Spugnini EP et al (2011) Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors. J Transl Med 9:221