Levetiracetam

From Dog

Levetiracetam is an anticonvulsant medication used to treat canine seizures, particularly status epilepticus[1].

This drug inhibits presynaptic calcium channels, resulting in impulse conduction impedance across synapses.

Recommended dose in dogs is 20 mg/kg orally every 8 hours[2][3].

References

  1. Hardy BT et al (2012) Double-masked, placebo-controlled study of intravenous levetiracetam for the treatment of status epilepticus and acute repetitive seizures in dogs. J Vet Intern Med 26(2):334-340
  2. Muñana KR et al (2012) Evaluation of levetiracetam as adjunctive treatment for refractory canine epilepsy: a randomized, placebo-controlled, crossover trial. J Vet Intern Med 26(2):341-348
  3. Fryer KJ et al (2011) Incidence of postoperative seizures with and without levetiracetam pretreatment in dogs undergoing portosystemic shunt attenuation. J Vet Intern Med 25(6):1379-1384