Affected dogs usually present with central neurological symptoms such as ataxia, circling, seizures and central blindness. Metastases within other organs may include other symptoms, often associated with vascular infiltration of organs with associated thromboembolism.
Diagnosis is based on clinical history and supportive evidence of tumors within the meninges, using CT or MRI imaging, which usually shows cyst-like structures and nodular enhancement within the subarachnoid space.
A definitive diagnosis usually requires histological examination of biopsied tissue samples.
Palliative responses may be achieved with parenteral dexamethasone or oral prednisolone, but because of the metastatic nature of these tumors, treatment is rarely instituted and the prognosis is usually poor.
- Tufts University
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