Monocillium spp

From Dog
Monocillium as viewed under the microscope[1]

Monocillium is an opportunistic filamentous deuteromycote mold normally found within the soil[2] and rarely causes disease in dogs.

Disease with this organism is thought to be acquired through inhalation, resulting in intracellular phagocytosis with subsequent widespread vascular dissemination.

Human infections has been reportedly associated with hypersensitivity pneumonitis[3] and carcinogenesis[4], although this has not been observed in dogs.

Speecies which are pathogenic to dogs include:

  • Monocillium indicum

In dogs, this fungus has reportedly caused fever, anorexia, diarrhea and lymphadenopathy. Postmortem examination revealed generalized lymphadenitis and splenitis[5].

Diagnosis is based on histological examination of biopsied material and visualization and identification of fungal hyphae.

No treatment has been reported with this disease.


  1. Lauren Kaln
  2. Girlanda M et al (2001) Impact of biocontrol Pseudomonas fluorescens CHA0 and a genetically modified derivative on the diversity of culturable fungi in the cucumber rhizosphere. Appl Environ Microbiol 67(4):1851-1864
  3. Cormier Y et al (1998) Hypersensitivity pneumonitis in peat moss processing plant workers. Am J Respir Crit Care Med 158(2):412-417
  4. Rank C et al (2011) Distribution of sterigmatocystin in filamentous fungi. Fungal Biol 115(4-5):406-420
  5. Mackie JT et al (2004) Granulomatous lymphadenitis and splenitis associated with Monocillium indicum infection in a dog. J Vet Diagn Invest 16(3):248-250