Neuroendocrine diseases are those which involve endocrine organs and result in paraneoplastic symptoms.
Affected dogs may present with hematological or cutaneous abnormalities such as secondary skin disease, cardiac irregularities (e.g. ventricular tachycardia), hematological changes, gastrointestinal disorders and neurological disease, depending on the underlying primary disease.
Canine disorders which can result in neuroendocrine disease include:
- Diabetes mellitus
- Hepatic neuroendocrine tumor
- Merkel cell carcinoma
- Pancreatic adenocarcinoma
- Pituitary adenoma
- Tappin S et al (2008) An intestinal neuroendocrine tumour associated with paroxysmal ventricular tachycardia and melaena in a 10-year-old boxer. J Small Anim Pract 49(1):33-37