From Dog

Niacinamide (Vitamin B3 is an essential vitamin which acts as a coenzyme in oxidation-reduction reactions.

This drug is often given in a combination form with tetracycline or doxycycline for treatment of a number of inflammatory immune-mediated skin diseases, including:

Recommended dose rates in dogs is 250 - 500 mg per dog orally once daily.


  1. Rosenkrantz WS (2004) Pemphigus: current therapy. Vet Dermatol 15(2):90-98
  2. Cornegliani L et al (2011) Sublingual reactive histiocytosis in a dog. J Vet Dent 28(3):164-170
  3. Hurn S et al (2005) Oral doxycycline, niacinamide and prednisolone used to treat bilateral nodular granulomatous conjunctivitis of the third eyelid in an Australian Kelpie dog. Vet Ophthalmol 8(5):349-352
  4. Rachid MA et al (2003) Concurrent follicular dysplasia and interface dermatitis in Boxer dogs. Vet Dermatol 14(3):159-166
  5. Mueller RS et al (2003) A retrospective study regarding the treatment of lupoid onychodystrophy in 30 dogs and literature review. J Am Anim Hosp Assoc 39(2):139-150
  6. Torres SM et al (2002) Dermal arteritis of the nasal philtrum in a Giant Schnauzer and three Saint Bernard dogs. Vet Dermatol 13(5):275-281