Octreotide

From Dog
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Octreotide is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone.

Other physiological effects include reduction of splanchnic blood flow, inhibition of release of serotonin, gastrin, vasoactive intestinal polypeptide, secretin, motilin, and pancreatic polypeptide.

Octreotide is primarily used in canine medicine for treatment of gastrinoma, insulinoma, osteosarcoma and acromegaly.

Recommended dose in dogs is 10 to 40 mg/kg every 8 to 12 hours.