In canine practice, orbifloxacin is indicated for the treatment of various infections, including urinary, skin, and otitis infections. It is specifically active against E. coli and Pseudomonas aeruginosa.
Recommended dose rate in dogs is 2.5 - 7.5 mg/kg given orally every 24 hours.
- Harada K et al (2012) Post-antibiotic effect of orbifloxacin against Escherichia coli and Pseudomonas aeruginosa isolates from dogs. Acta Vet Scand 54:16
- Awji EG et al (2012) Comparative mutant prevention concentration and mechanism of resistance to veterinary fluoroquinolones in Staphylococcus pseudintermedius. Vet Dermatol 23(4):376-380