Oxfendazole

From Dog

Oxfendazole is a benzimidazole anthelmintic used for parasite control in dogs.

This drug has similar pharmacokinetics to other benzimidazoles such as fenbendazole and albendazole[1].

It has proven efficacy against the metacestode stages of Echinococcus multilocularis, Echinococcus granulosus, Taenia hydatigena[2]various lungworm species, Giardia spp, Oslerus osleri[3] and Tritrichomonas spp.

Few side effects have been reported with this drug, and is usually a dose-related gastroenteritis when recommended doses are exceeded.

Recommended dose in dogs is 10 - 20 mg/kg orally once daily for three days[4].

References

  1. Gokbulut C et al (2007) Comparative plasma disposition of fenbendazole, oxfendazole and albendazole in dogs. Vet Parasitol 148(3-4):279-287
  2. Gemmell MA et al (1979) The effect of oxfendazole on Echinococcus granulosus and Taenia hydatigena infections in dogs. Res Vet Sci 26(3):389-390
  3. Bourdoiseau G et al (1994) Oslerosis of the dog: diagnostic and therapeutic status. Parasite 1(4):369-378
  4. Villeneuve V et al (2000) Efficacy of oxfendazole for the treatment of giardiosis in dogs. Experiments in dog breeding kennels. Parasite 7(3):221-226