Parathyroid adenoma

From Dog
A proliferative non-invasive parathyroid adenoma, histological appearance[1]

Parathyroid adenoma are a benign tumor of the canine parathyroid gland characterized by hyperparathyroidism.

These tumors are far more common than parathyroid carcinoma and parathyroid hyperplasia, and appear as typically small, well-encapsulated light brown to red tumors located in close approximation to the thyroid gland.

Affected dogs typically present with a small palpable tumor in the cervical neck region and clinical symptoms associated with hyperparathyroidism, including polydipsia, polyuria, reduced activity, and stiff gait.

Laboratory findings include moderate to extensive hypercalcemia, low or low-normal serum phosphorus concentrations and normal or increased serum parathyroid hormone concentrations[2].

Diagnosis is usually based on presenting clinical and laboratory signs, confirmed by histological examination of parathyroid biopsies[3].

Treatment is usually curative with bilateral thyroidectomy and usually have a good prognosis.

For further details, see hyperparathyroidism.

References

  1. Schaefer C & Goldstein RE (2009) Canine primary hyperparathyroidism. Compend Contin Educ Vet 31(8):382-390
  2. Jores K & Kessler M (2011) Primary hyperparathyroidism in the dog. Diagnosis, therapy and postoperative management in 19 dogs. Tierarztl Prax Ausg K Kleintiere Heimtiere 39(6):389-396
  3. Liles SR et al (2010) Ultrasonography of histologically normal parathyroid glands and thyroid lobules in normocalcemic dogs. Vet Radiol Ultrasound 51(4):447-452