Pentamidine isethionate

From Dog

Pentamidine isethionate is an alternative treatment for Babesia canis infections.

This antimicrobial drug also has efficacy against Trypanosoma congolense[1]. It appears superior to diminazene aceturate against this parasite[2].

Recommended dose rate is 16 mg/kg given intramuscularly every 24 hours for 2 doses.

References

  1. Desquesnes M et al (2012) Atypical hyperpachymorph Trypanosoma (Nannomonas) congolense forest-type in a dog returning from Senegal. Parasite 19(3):239-247
  2. Akpa PO et al (2008) Comparative efficacy assessment of pentamidine isethionate and diminazene aceturate in the chemotherapy of Trypanosoma brucei brucei infection in dogs. Vet Parasitol 151(2-4):139-149