Peptostreptococcus spp

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Electron micrograph of Peptostreptococcus spp[1]

Peptostreptococcus spp are a Gram-positive, anaerobic, zoonotic commensal bacteria which is a commensal in the oropharynx, skin, gastrointestinal, vagina and urinary tracts, and compose a portion of the bacterial gut flora.

These bacteria have a predilection for anaerobic sites and a tendency to purulent disease and can cause zoonotic disease via bite wounds or licking, especially in immunocompromised humans.

Disease can spread systemically, usually via hematogenous routes.

Species which have been reported in dogs include:

  • Peptostreptococcus productus
  • Peptostreptococcus magnus
  • Peptostreptococcus tetradius
  • Finegoldia magna[2]

Localized infections such as ulcerative keratitis[3], periodontitis[4] and pyoderma[5] and associated with bite-wound abscess[6] are common.

In dogs, they are sometimes involved in systemic diseases such as empyema, osteomyelitis[7][8] and meningitis[9] .

Diagnosis is usually based on bacterial culture and speciation via PCR assays[10].

Treatment is usually effective with amoxycillin/clavulanate, metronidazole, clindamycin, doxycycline, gentamycin, and sulfa-trimethoprim[11].


  1. Vietsciences
  2. Lee S et al (2008) A case of necrotizing fasciitis due to Streptococcus agalactiae, Arcanobacterium haemolyticum, and Finegoldia magna in a dog-bitten patient with diabetes. Korean J Lab Med 28(3):191-195
  3. Ledbetter EC & Scarlett JM (2008) Isolation of obligate anaerobic bacteria from ulcerative keratitis in domestic animals. Vet Ophthalmol 11(2):114-122
  4. Ferreira FB et al (2006) Root canal microbiota of dogs' teeth with periapical lesions induced by two different methods. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102(4):564-570
  5. Price PM (1991) Pyoderma caused by Peptostreptococcus tetradius in a pup. J Am Vet Med Assoc 198(9):1649-1650
  6. Meyers B et al (2008) The bacteriology and antimicrobial susceptibility of infected and non-infected dog bite wounds: fifty cases. Vet Microbiol 127(3-4):360-368
  7. Johnson KA et al (1984) Osteomyelitis in dogs and cats caused by anaerobic bacteria. Aust Vet J 61(2):57-61
  8. Hodgin EC et al (1992) Anaerobic bacterial infections causing osteomyelitis/arthritis in a dog. J Am Vet Med Assoc 201(6):886-888
  9. Dow SW et al (1988) Central nervous system infection associated with anaerobic bacteria in two dogs and two cats. J Vet Intern Med 2(4):171-176
  10. Wang RF et al (1996) PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples. Appl Environ Microbiol 62(4):1242-1247
  11. Radice M et al (2006) Evaluation of subgingival bacteria in the dog and susceptibility to commonly used antibiotics. J Vet Dent 23(4):219-224