Phenylbutazone

From Dog

Phenylbutazone is an anti-inflammatory drug that was commonly used in dogs for peri-operative pain[1] and osteoarthritis[2] before the advent of safer drugs such as meloxicam and carprofen[3].

Side-effects of this drug included gastrointestinal bleeding, blood dyscrasias and myelofibrosis[4].

Recommended dose rate is 3 - 7 mg/kg given orally once to three time daily.

References

  1. Joubert KE (2001) The use of analgesic drugs by South African veterinarians. J S Afr Vet Assoc 72(1):57-60
  2. Watson AD et al (1996) Use of anti-inflammatory and analgesic drugs in dogs and cats. Aust Vet J 74(3):203-210
  3. Fox SM & Johnston SA (1997) Use of carprofen for the treatment of pain and inflammation in dogs. J Am Vet Med Assoc 210(10):1493-1498
  4. Weiss DJ & Smith SA (2002) A retrospective study of 19 cases of canine myelofibrosis. J Vet Intern Med 16(2):174-178