Progressive retinal atrophy - dominant
Autosomal dominant progressive retinal atrophy (PRA-D) is an autosomal-dominant genetic disease characterised by degeneration of the photoreceptor cells in the retina, eventually leading to complete blindness.
This form of PRA has an age of onset of around 4 months of age.
A breed-specific PCR test is available for testing for this condition.
There is no known treatment for this condition and severely affected individual dogs often remain blind.
- Petit L et al (2012) Restoration of Vision in the pde6β-deficient Dog, a Large Animal Model of Rod-cone Dystrophy. Mol Ther 20(11):2019-2030