Diagnosis is based on clinical symptoms, evidence of caudal abdominal pain, rectal confirmation of prostatomegaly, organomegaly (especially enlarged liver and spleen) and imaging studies to show a large dyshomogenous prostate and more rare findings such as bilateral hydronephrosis.
A definitive diagnosis requires fine-needle aspiration of prostatic tissue or exploratory laparotomy biopsy of the prostate.
Treatment may be difficult in these cases as most are refractory to surgical intervention via prostatectomy, which is a successful treatment of human patients.
Complete remission has been reported with multi-drug chemotherapy, and adjunct radiation therapy may assist survival in these cases.
Prognosis is guarded in most cases.
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- Chen B et al (2012) A new marker, SOX11, aids the diagnosis of mantle cell lymphoma in the prostate: A case report. Oncol Lett 4(2):265-267
- Assin R et al (2008) Prostate as sole unusual recurrence site of lymphoma in a dog. In Vivo 22(6):755-757