Prostatic squamous metaplasia
From Dog
Fine needle aspirate from a canine prostate with squamous metaplasia. The smear contains numerous well-differentiated squamous cells with varying degrees of keratinisation. Most squamous cells exhibit a low nucleus: cytoplasm ratio and contain abundant pale to basophilic cytoplasm. Mild suppurative inflammation and blood contamination are also present[1]
Prostatic squamous metaplasia is a rare prostate disease of male dogs.
The most dramatic forms of squamous metaplasia occur with exposure to estrogens or in feminizing syndrome[2].
Diagnosis is based on histological analysis of prostatic biopsies[3] done by exploratory laparotomy or ultrasound guided percutaneous sampling.
A differentail diagnosis would include prostatic atrophy. prostatitis, prostatic hyperplasia and prostatic adenocarcinoma[4].
There is no known treatment for this disease other than correction of underlying hormonal disorders.
References
- ↑ Ireland Veterinary Journal
- ↑ O'Shea JD (1963) Squamous metaplasia of the canine prostate gland. Res Vet Sci 4:431-434
- ↑ Powe JR et al (2004) Evaluation of the cytologic diagnosis of canine prostatic disorders. Vet Clin Pathol 33(3):150-154
- ↑ Orgad U et al (1984) Histochemical studies of epithelial cell glycoconjugates in atrophic, metaplastic, hyperplastic, and neoplastic canine prostate. Lab Invest 50(3):294-302
