This disorder, which occurs primarily in young pups, involve parasite-induced neuritis of peripheral nerves and skeletal muscle neuromuscular junctions which results in progressive paralysis, myositis and muscular rigidity of the hindlimbs.
- Neospora caninum
- Toxoplasma gondii
- Sarcocystis neurona
- Ehrlichia canis
- Hepatozoon canis
- Leishmania infantum
Clinically affected pups usually present with progressive stiffness, paresis with muscle wasting, hyporeflexia and extensor rigidity, usually of the pelvic limbs. Neural reflexes are often diminished.
A presumptive diagnosis is based on demonstration of anti-Neospora or anti-Toxoplasma antibodies in serum and response to antimicrobial therapy.
In pups with pelvic limb rigidity, the prognosis is guarded due to extensive nerve damage.
- Wouda W et al (1993) Neospora caninum as a cause of lameness symptoms in young dogs. Tijdschr Diergeneeskd 118(12):397-401
- Vashisht K et al (2005) Naturally occurring Sarcocystis neurona-like infection in a dog with myositis. Vet Parasitol 133(1):19-25
- Paciello O et al (2009) Canine inflammatory myopathy associated with Leishmania Infantum infection. Neuromuscul Disord 19(2):124-130
- Saey V et al (2010) Neuritis of the cauda equina in a dog. J Small Anim Pract 51(10):549-552
- Cuddon P et al (1992) Neospora caninum infection in English Springer Spaniel littermates. Diagnostic evaluation and organism isolation. J Vet Intern Med 6(6):325-332
- Wolf M et al (1991) The clinical diagnosis of protozoal myositis syndrome (Neospora caninum) of puppies. Tierarztl Prax 19(3):302-306