Schizophyllum spp are a filamentous basidiomycetous fungus which is normally found as a commensal on rotting vegetation.
Schizophyllum is a mushroom that colonizes rotting wood and has a wide global distribution. It maintains itself via a complex life cycle that includes fruiting bodies (mushrooms), basidia, basidiospores, homokayons and dikaryons.
Humans have been frequently infected by this fungus, with respiratory disease the primary complaint.
Dogs are thought to become infected from mycelia penetrating wounds.
Schizophyllum are an opportunistic pathogen that causes infections characterized by progressive subcutaneous granulomatous lesions in the subcutaneous tissues as well as disseminated visceral infections.
Species which are pathogenic to dogs include:
- Schizophyllum commune
Diagnosis can be ascertained by microscopic identification of the fungus or by PCR assay speciation. Lymph nodes characteristically contain PAS positive fungal elements and portions of tissue culture produce mycelial fungal growth.
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