Difference between revisions of "Budesonide"

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Budesonide is a medium-acting [[corticosteroid]] similar to [[betamethasone]].
 
Budesonide is a medium-acting [[corticosteroid]] similar to [[betamethasone]].
  
This drug is indicated for treatment of [[bronchitis]] and [[irritable bowel disease]]<ref>Pietra M ''et al'' (2013) Plasma concentrations and therapeutic effects of budesonide in dogs with inflammatory bowel disease. ''Am J Vet Res'' '''74(1)''':78-83</ref> and as a topical drug for treatment of [[atopy]]<ref>Olivry T & Bizikova P (2013) A systematic review of randomized controlled trials for prevention or treatment of atopic dermatitis in dogs: 2008-2011 update. ''Vet Dermatol'' '''24(1)''':97-117</ref>.
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This drug is indicated for treatment of [[bronchitis]]<ref>Melamies M ''et al'' (2012) Endocrine effects of inhaled budesonide compared with inhaled fluticasone propionate and oral prednisolone in healthy Beagle dogs. ''Vet J'' '''194(3)''':349-353</ref> and [[irritable bowel disease]]<ref>Pietra M ''et al'' (2013) Plasma concentrations and therapeutic effects of budesonide in dogs with inflammatory bowel disease. ''Am J Vet Res'' '''74(1)''':78-83</ref> and as a topical drug for treatment of [[atopy]]<ref>Olivry T & Bizikova P (2013) A systematic review of randomized controlled trials for prevention or treatment of atopic dermatitis in dogs: 2008-2011 update. ''Vet Dermatol'' '''24(1)''':97-117</ref>.
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The main side-effects with this drug is suppression of the pituitary-adrenal function<ref>Stroup ST ''et al'' (2006) Effects of oral administration of controlled-ileal-release budesonide and assessment of pituitary-adrenocortical axis suppression in clinically normal dogs. ''Am J Vet Res'' '''67(7)''':1173-1178</ref>.
  
 
Recommended dose rate in dogs is 3 mg/m<sup>2</sup> given orally once daily.
 
Recommended dose rate in dogs is 3 mg/m<sup>2</sup> given orally once daily.

Revision as of 01:17, 2 April 2013

Budesonide is a medium-acting corticosteroid similar to betamethasone.

This drug is indicated for treatment of bronchitis[1] and irritable bowel disease[2] and as a topical drug for treatment of atopy[3].

The main side-effects with this drug is suppression of the pituitary-adrenal function[4].

Recommended dose rate in dogs is 3 mg/m2 given orally once daily.

References

  1. Melamies M et al (2012) Endocrine effects of inhaled budesonide compared with inhaled fluticasone propionate and oral prednisolone in healthy Beagle dogs. Vet J 194(3):349-353
  2. Pietra M et al (2013) Plasma concentrations and therapeutic effects of budesonide in dogs with inflammatory bowel disease. Am J Vet Res 74(1):78-83
  3. Olivry T & Bizikova P (2013) A systematic review of randomized controlled trials for prevention or treatment of atopic dermatitis in dogs: 2008-2011 update. Vet Dermatol 24(1):97-117
  4. Stroup ST et al (2006) Effects of oral administration of controlled-ileal-release budesonide and assessment of pituitary-adrenocortical axis suppression in clinically normal dogs. Am J Vet Res 67(7):1173-1178