Diphenoxylate

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Diphenoxylate is an opioid agonist that works similar in action on the gastrointestinal tract to loperamide, resulting in delayed peristalsis[1].

It is commonly used in dogs with chronic diarrhea associated with ulcerative colitis.

References

  1. Mir GN et al (1978) In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide. Arzneimittelforschung 28(8a):1448-1454