Epstein-Barr virus

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Epstein-Barr virus (EBV) is a herpesvirus which infects humans and causes glandular fever (infectious mononucleosis).

Dogs are commonly exposed to this virus via aerosol transmission from humans, but rarely develop symptoms associated with viremia.

Seroprevalence of exposure to the virus in dogs has been reported commonly across the world[1].

In most cases of canine infection with EBV, mild pharyngitis and tonsillitis may be observed, associated with viral proliferation in pharyngeal tonsil, but there is no evidence of EBV in canine peripheral blood mononuclear cellsCite error: Invalid <ref> tag; refs with no name must have content.

However, recent researched has alluded to the development of malignant lymph nodes of dogs with lymphoma associated with EBV, underlying the role of this virus in neoplasia as is observed with humans[2].

Diagnosis is based on PCR identification of the virus on tonsillar swabs.

References

  1. Milman G et al (2011) Serological detection of Epstein-Barr virus infection in dogs and cats. Vet Microbiol 150(1-2):15-20
  2. Huang SH et al (2012) Evidence of an oncogenic gammaherpesvirus in domestic dogs. Virology. 2012 Jun 5;427(2):107-17