Fusarium spp

From Dog
Revision as of 22:10, 1 March 2013 by WikiSysop (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Fusarium macroconidia under light microscopy

Fusarium spp are a zoonotic fungus which causes dermatophytosis in dogs as well as food-spoilage mycotoxicosis[1].

Species which are pathogenic in dogs include:

  • Fusarium sporotrichioides
  • Fusarium solani

Clinically affected dogs usually present with ulcerative lesions anywhere on the skin. Paronychia is a common presentation.

In food-borne mycotoxicosis, consumption of grains naturally contaminated with Fusarium mycotoxins can adversely affect dogs' feeding behaviors and metabolism[2]. The main active toxin, zearalenone, is an estrogenic metabolite which causes profound regressive lesions in the ovarian granular cells, leading to degeneration, atrophy and resultant infertility[3].

A second mycotoxin which has been reported in this species is trichothecene, which reportedly causes primarily gastrointestinal effects such as diarrhea[4].

Systemic diseases associated with this fungus have been reported, with cutaneous and submucosal nodules and pyogranulomatous kidney lesions[5].

Central nervous system disease has also been reported, with meningoencephalitis observed[6].

Chronic ulcerative fusarium infection has been reported in a dog with immune-mediated hemolytic anemia[7].

This dermatophytosis appears to respond to itraconazole.


  1. Leung MCet al (2007) Effects of foodborne Fusarium mycotoxins with and without a polymeric glucomannan mycotoxin adsorbent on food intake and nutrient digestibility, body weight, and physical and clinicopathologic variables of mature dogs. Am J Vet Res 68(10):1122-1129
  2. Golinski PK & Nowak T (2004) Dietary origin of mycotoxins with estrogenic potential and possible health implications to female dogs. Pol J Vet Sci 7(4):337-341
  3. Gajecka M et al (2008) Histopathological examination of ovaries in bitches after experimental zearalenone mycotoxicosis. Pol J Vet Sci 11(4):363-366
  4. Bhat RV et al (1995) Outbreak of trichothecene mycotoxicosis associated with consumption of mould-damaged wheat production in Kashmir Valley, India. Lancet 1(8628):35-37
  5. Kano R et al(2002) Isolation of Fusarium solani from a dog: identification by molecular analysis.
  6. Evans J et al (2004) Intracranial fusariosis: a novel cause of fungal meningoencephalitis in a dog. Vet Pathol 41(5):510-54
  7. Kano R et al (2011) Chronic ulcerative dermatitis caused by Fusarium sporotrichioides. Med Mycol 49(3):303-305