Lymphadenopathy refers to any disease which causes a change in the size or palpable consistency of a lymph node.
A single lymph node may be involved (localized or peripheral lymphadenopathy) or a number of lymph nodes may be involved (multicentric lymphadenopathy).
Additionally, peripheral lymphadenopathy refers to enlarged lymph nodes in peripheral sites such as pre-scapular, retropharyngeal, submandibular and popliteal lymph nodes.
Numerous diseases are capable of causing lymphadenopathy, including:
- neoplasia - e.g. multicentric lymphosarcoma
- viral diseases - e.g. canine adenovirus (distemper)
- bacterial diseases