Oxytocin

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Oxytocin is a neuropeptide produced by the pituitary in response to labor.

This drug causes strong, coordinated contractions of the estrogen-primed uterus.

Oxytocin is used primarily in dogs for treatment of dystocia.

Recommended dose rate is 0.25 IU every 2 hours. Larger doses may cause uterine tetany[1].

Oxytocin does not dissociate readily from myometrial receptors, so there is little wisdom in continuing treatment if labor does not progress[2].

References

  1. Davidson AP (2001) Uterine and fetal monitoring in the bitch. Vet Clin North Am Small Anim Pract 31:305-313
  2. M. Kustritch, DVM