Paecilomyces spp are an opportunistic fungal infection of dogs with immunocompromised states.
Species which are pathogenic include:
Generalized calcinosis cutis, pneumonia, discospondylitis and systemic phaeohyphomycosis have been reported with this fungus. In one case focal granulomas were observed in the skin, liver and spleen.
Thick walled fungal hyphae are usually detected in impression smears from skin lesions, kidneys, mitral valve, abdominal aorta and vertebral discs. Staining with periodic acid-Schiff's stain is usually confirmatory.
Treatment with generalized phaeohyphomycosis usually requires parenteral ketoconazole.
The prognosis for paecilomycosis is poor, although some treatment success has been reported.
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