From Dog

Paratuberculosis (Johne's disease) is a rare gastrointestinal disease of dogs caused by Mycobacterium avium sub paratuberculosis [1].

Dogs commonly infected by this bacteria are urban or farm dogs, with symptoms of chronic gastrointestinal disease characterized by vomiting, weight loss and diarrhea. Exposure to feces from cattle infected with Johne's Disease may predispose to infections in dogs.

Diagnosis is based on PCR identification of M. avium sub paratuberculosis from endoscopic intestinal biopsies or fecal samples.

Histopathology is often indicative of chronic inflammatory bowel disease[2].

A differential diagnosis would include other causes of diarrhea as well as ulcerative colitis.

Treatment is cymptomatic, with drugs such as clarithromycin indicated as a primary antimicrobial against this mycobacteria.


  1. Vogel O (1977) Paratuberculosis in a dog. Berl Munch Tierarztl Wochenschr 90(21):419-421
  2. Glanemann B et al (2008) Detection of Mycobacterium avium subspecies paratuberculosis-specific DNA by PCR in intestinal biopsies of dogs. J Vet Intern Med 22(5):1090-1094