Pharmacy

Below are listed some of the common drugs used in canine medicine. See the FDA Green book for a comprehensive list of approved veterinary medicines.

Drug	Indications	Dose	Route	Frequency
Acarbose	Diabetes mellitus	12.5 - 20 mg	Oral	with each meal
Acemannan	Immunomodulation	1 - 2 mg/kg	Intralesional, IP or SQ	weekly
Acepromazine	Sedation, restraint	0.05 - 2.25 mg/kg	SQ, IM, PO	q 8 - 12hrs
	Aortic thromboembolism	0.15 - 0.3 mg/kg	SQ	q 8 - 12hrs
	Amphetamine and pseudoephedrine toxicosis	0.05 -1.0 mg/kg	IV, IM, SQ	q 8 - 12hrs
Acetazolamide	Glaucoma	5 - 10 mg/kg	PO	q 8 - 12hrs
Acetylcysteine	Mucolytic (Asthma), Acetaminophen toxicity	140 mg/kg	IV	loading dose
		5 - 10 mg/kg	PO	every 12 hours
Acetylsalicylic acid	Antipyretic	6 - 10 mg/kg	PO	q 48 - 72hrs
	Antithrombotic	25 mg/kg	PO	2 times/wk
	Anti-inflammatory	10 - 20 mg/kg	PO	q 48 hrs
	Analgesia	10 mg/kg	PO	q 48hrs
Actinomycin D	Chemotherapy / antimicrobial	0.5 - 0.9 mg/m2	IV	once every 3 weeks
S-Adenosylmethionine	Glutathione replenisher - chronic hepatitis, hepatic encephalopathy, portosystemic shunt	20 - 30 mg/kg	PO	q 24hrs
Aglepristone	Mesalliance	10mg/kg	SQ	stat
Albendazole	Lungworm	50 mg/kg	PO	daily for 21 days
Albuterol sulphate	Bronchodilation	90 µg metered dose	inhaler	q 6 - 8hrs
Alfaxan	general anesthesia	1 - 2 mL per 5 kg bodyweight	IV	bolus or slowly IV
Allopurinol	Urate uroliths	10 mg/kg	PO	q 8 - 12hrs for 30 days
Alprazolam	Anxiolytic	0.125 - 0.25 mg/dog	PO	q 12hrs
Aluminium carbonate gel	Phosphate binder	10 - 30 mg/kg	PO with meals	q 8hrs
Aluminium hydroxide	Antacid	20 - 30 ml	PO	q 2 - 4 hrs
	Phosphate binder	30 - 90 mg/kg	PO with meals	q 8 - 24 hrs
Amantadine	Analgesia for chronic pain	3 - 5 mg/kg	PO	daily for 7 - 14 days
Amikacin	Susceptible infections	15 - 22 mg/kg	IM, IV, SQ	q 24hrs
Aminophylline	Asthma	4 - 6.6 mg/kg	PO	q 8 - 12hrs
		2 - 5 mg/kg	IV infusion	q 12hrs
5-aminosalicylic acid	ulcerative colitis	20 mg/kg	PO	q 24 hrs
Amitriptyline (Endep-10)	Analgesia	2 mg/kg	PO	q 24 hrs
Amlodipine besylate	Systemic hypertension	0.625 mg	PO	q 24 hrs
Ammonium chloride	Struvite dissolution	800 mg	PO	q 24 hrs
Amoxicillin/clavulanate	Susceptible infections	10 - 20 mg/kg	PO	q 12 hrs
Amoxil	Susceptible infections	4 - 11 mg/kg	PO	q 12 hrs
Amphetamine	CNS stimulation during certain toxicoses	5 mg	PO	q 12 hrs
Amphotericin B	Systemic mycoses	0.15 - 1 mg/kg in 5% dextrose	IV	q 48 hrs to a total cumulative dose of 10mg/kg
			SQ	diluted 1:10 in saline
Ampicillin	Susceptible infections	20 - 60 mg/kg	PO	q 8 - 12 hrs
Amprolium	Coccidiosis	60 - 100 mg/kg	PO	q 24 hrs x 5 d
	With sulfadimethoxine	150 mg/kg	PO	q 24 hrs x 5d
Ascorbic acid	Antioxidant	25 - 125 mg/kg/day	PO	q 24hrs
	Acetaminophen toxicosis	30 mg/kg	PO, SQ	6 - 7 treatments
Asparaginase	Lymphosarcoma	10,000 U/m2	IV	weekly as part of a protocol
Aspirin	Antipyretic	6 - 10 mg/kg	PO	q 48 - 72hrs
Atenolol	ß1-blocker for Hypertrophic cardiomyopathy + Hypertension	6.25 mg/cat	PO	q 24hrs
Atipamezole	Medetomidine reversal	equivolume	IM	as needed
Atovaquone	Toxoplasma spp, Babesia spp, Pneumocystis spp	10 - 15 mg/kg with fatty meal	PO	q 8 hrs x 21 days
Atracurium	Paralytic anaesthetic agent	0.1 - 0.25 mg/kg	IV	repeated q 30mins
Atropine	Pre-anaesthetic medicant, Sinus bradycardia	0.02 - 0.04 mg/kg	IM, IV, SQ	as required
	Organophosphate toxicity	0.2 - 2.0 mg/kg	IM, SQ	q 2hrs
Aurothioglucose	Pemphigus, periodontitis and pododermatitis	1 - 2 mg	IM	weekly
Azathioprine	Enteritis	0.2 -0.3 mg/kg	PO	q 24 - 48hrs
	Immune-mediated haemolytic anaemia	1 mg/kg	PO	q 24 - 48hrs
	Immunosuppression	1.1 mg/kg	PO	q 48hrs
Azithromycin	Susceptible infections	5 mg/kg	PO	q 24 - 48 hrs
	Susceptible infections	80 mg stat	PO	weekly x 3
Azodyl	Probiotic	1 capsule	PO	q 12 - 24 hrs
Aztreonam	Susceptible infections	12 - 25 mg/kg	IV, IM	q 8 - 12 hrs
Baytril	Susceptible infections	5.0 - 20.0 mg/kg	PO, SQ, IM, IV (with caution - may cause blindness)	q 24hrsfor 7 - 10 days
Beclomethasone	Anti-inflammatory	200 mg	Inhalant	as required
Benazepril	Afterload reduction (chronic renal disease, congestive heart failure)	0.25 - 0.5 mg/kg	PO	q 24hrs
Benzimidazole	Trypanosomiasis	5 mg/kg	PO	q 24hrs for 4 months
Benzocaine	Local anaesthetic	1 - 5 ml	SQ	as required
Benzoyl peroxide	Seborrhoea, antibacterial	leave on skin for 10mins		q 3 - 4 days for 2 weeks
Betamethasone	Anti-inflammatory	0.1 - 0.2 mg/kg	PO	q 12 - 24hrs
Bethanechol	Bladder atony, dysautonomia, cystitis	1.25 - 5.0 mg	PO	q 8- 12 hrs
Bisacodyl	Constipation	2 - 5 mg/dog	PO	q 24hrs as needed
Bleomycin	Chemotherapy	10 µg/m2	IV, SQ	q 24hrs for 4 days, then weekly; max dose 200mg/m2
Bran	Stool softener	1 - 2 teaspoons/400g food	PO	as needed
Brewer's yeast	B vitamin source	0.2 mg	PO	q 24 hrs
Bromhexine hydrochloride	Mucolytic for asthma	2 mg/kg	PO	q 12 hrs for 7 - 10 days
Bromide	Anticonvulsant	30 - 60 mg/kg	PO	q 12 hrs
Bromocriptine	Cushing's syndrome, False pregnancy, lactation cessation	10 - 30 µg/kg	PO	q 24 hrs for 10 - 16 days
Budesonide	Asthma, ulcerative colitis	1 mg/dog	PO	daily
Bunamidine	Cestodes - Taenia spp, Spirometra spp, Diphyllobothrium spp	20 - 50 mg/kg	PO	after 3 hr fast
Bupivicaine hydrochloride	Local Anaesthetic	0.22 - 3.0 ml/cat	Epidural	stat
Buprenorphine	Opioid analgesia	0.005 - 0.01 mg/kg	IV, IM	q 4 - 8 hrs
Buspirone	Behavioural therapy	0.5 - 1.0 mg/kg	PO	q12-24hrs
Busulfan	Chronic myelocytic leukaemia	3 - 4mg/m2 or 0.1 mg/kg	PO	q 24 hrs
Butorphanol	Preanesthetic	0.05 - 0.4mg/kg with ACP	IV, IM, SQ
	Antiemetic	0.2 - 0.6 mg/kg	SQ, IM, IV
	Analgesia	0.1 - 0.8 mg/kg	PO	q 6 - 12 hrs
Cabergoline	Induction of estrus/abortion/pyometra	5 μg/kg/day	PO, SQ	q 24 hrs
Calcitriol	Hypoparathyroidism, hyperparathyroidism	1.5 - 3.0 ng/kg	PO	q 24 hrs
Calcium carbonate	Nutritional supplement	1/2 tsp	PO	daily
	Phosphate binder	60 - 100 mg/kg	PO	daily
Calcium chloride 10%	Ventricular asystole	1 ml/9kg or 0.1 - 0.3ml/kg	IV (slowly)	stat
	Hypocalcaemia	1 ml/9kg	IV	stat
Calcium citrate	Calcium replacement, cystitis	10 - 30 mg/kg	PO	q 8 hrs
Calcium EDTA	Lead poisoning	100 mg/kg/day	SQ	daily for 5 days
Calcium gluconate	Ventricular asystole	0.5 - 1.5 ml/kg	IV (slowly)	as required
	Hypocalcemia, hyperkalemia	0.5 - 1.5 ml/kg	IV (slowly)	as required
Capstar	Fleas	1 tab	PO	daily as needed
Captopril	Vasodilator	2 - 3 mg/dog	PO	q 8 - 12 hrs
		3 - 6.25 mg/dog	PO	q 12 hrs
Carbenicillin	cystitis	10 - 55 mg/kg	PO	q 8hrs
Carboplatin	Chemotherapy	200 mg/m2	IV	q 4 weeks
Carmustine	Chemotherapy	50 mg/m2	IV	q 6 weeks
Carprofen	Analgesia	1 - 4 mg/kg	SQ	stat
		0.5-1.0 mg/kg	PO	q 24hrs
Cartrofen	Analgesia	1 - 4 mg/kg	SQ	stat
Cefadroxil	Susceptible infections	10 mg/kg	PO	q 24 hrs for 1 - 4 weeks
Cefovecin	Susceptible infections	8 mg/kg (0.5 cc)	SQ	q 2 weeks x 3
Cephalexin	Susceptible infections	10 - 35 mg/kg	PO	q 8 - 12 hrs
Cerenia	Anti-emetic	1.0 mg/kg	SQ/PO	q 24 hrs for 4 days, then rest 2 days
Charcoal, activated	Adsorbent for poisonings	1 - 8 g/kg	PO	as needed
Chlorambucil	Chemotherapy, ulcerative colitis	0.1 - 0.5 mg/kg	PO	q 48 - 72 hrs
	pemphigus	0.1 - 0.2 mg/kg	PO	q 48 hrs with prednisolone
Chloramphenicol	Susceptible infections	10 mg/kg	PO	q 12hrs
Chlorhexidine 0.5%	Burns	dilute 1:40 with saline	topically	q 24hrs
Chlorothiazide	Diuretic	10 - 40 mg/kg	PO	q 12 hrs
	Partial ADH deficiency	20 - 40 mg/kg	PO	q 12 hrs
Chlorpheniramine	Antihistamine	1 - 2 mg/dog	PO	q 8 - 12 hrs
Chlorpromazine	vomiting, pancreatitis	0.2 - 0.5 mg/kg	IM or SQ	q 6-8hrs
Cholecalciferol (Vit D)	hyperparathyroidism, hypocalcaemia	500 - 2000 U/kg	PO	q 24 hrs
Chondroitin	Arthritis	50 - 100 mg/dog	PO	q 24 hrs
Cimetidine	Oesophagitis, antiemetic, gastritis	5 - 15 mg/kg	PO, IV, IM	q 8 - 12 hrs
Ciprofloxacin	Susceptible infections	11 - 15 mg/kg	PO	q 24 hrs
Cisapride (Prepulsid)	constipation, megacolon	0.5 - 5.0mg/cat	PO	q 12 hrs
Cisplatin	Chemotherapy	100 mg/m2	IV	q 4 weeks x 2
Clarithromycin	Mycobacterium spp	50 mg/dog	PO	q 12 hrs
Clavulox	Susceptible infections	10 - 20 mg/kg	PO	q 12 hrs
Clindamycin	Anaerobic infections	5 - 11 mg/kg	PO	q 12 hrs
	Stomatitis, Pancreatitis	22 mg/kg	PO	q 24 hrs
	Exocrine pancreatic insufficiency	5 - 10 mg/kg	PO	q 6 - 8 hrs
	Enteroepithelial cycle	12.5 - 50 mg/kg	PO	q 12 hrs
Clofazimine	Mycobacterium spp	4 - 8 mg/kg	PO	q 24 hrs for 6 weeks
		50 mg/cat	PO	q 48 hrs
Clomipramine	obsessive compulsive disorders, aggression	0.5 - 2.0 mg/kg	PO	q 12 - 24 hrs
Clonazepam	Seizures, obsessive compulsive disorders, separation anxiety	0.5 mg/kg	PO	q 8 - 12 hrs
Clopidogrel	thromboembolism, hypertrophic cardiomyopathy	18.75 - 75 mg	PO	q 24 hrs
Clorazepate	separation anxiety	1 - 2 mg/kg	PO	q 8 - 12 hrs
Clotrimazole	Fungal infections	apply to lesion	topical	q 12 hrs
	Fungal infections	60 ml of 1 g/dL of polyethylene glycol intranasal		over 1 hr under general anaesthesia
Cloxacillin	Susceptible infections	20 - 40 mg/kg	PO, IM, IV	q 4 - 8 hrs
Coal tar shampoos	Seborrhoea	Keep in contact with skin for 10 mins	Topically	q 24 hrs
Cobalamin	see Vit B12
Cod liver oil		1 teaspoon / 10 kg
Codeine	Pain relief	0.5 - 4 mg/kg	PO	q 6 - 12 hrs
	Antitussive, analgesia	0.1 - 0.3 mg/kg	PO	q 4 - 6 hrs
Colchicine	Antifibrotic	0.01 - 0.3 mg/kg	PO	q 4 - 6 hrs
Colony stimulating factor	cyclic neutropenia	2.5 - 5.0 mg/kg (3 × 107 IU/kg)	SQ	q 24 hrs
Convenia	Susceptible infections	8 mg/kg (0.5 cc)	SQ	q 2 weeks x 3
Corticotrophin gel (ACTH)	Response test	pre-ACTH sample 0.5 - 2.2 IU/kg	IM
Cortisone acetate	hypoadrenocorticism	1 mg/kg	PO, IM	q 24 hrs
Cosyntropin	pre-ACTH sample	0.125 mg/dog	IV
Cyanocobalamin	Vit B12 deficiency	50 - 1000 µg	PO, IM, SQ	q 24 hrs
Cyclizine	Antiemetic	4 mg/kg	IM	q 8 hrs
Cyclophosphamide	Chemotherapy	100 mg/m2	PO	q 3 weeks with doxorubicin
Cyclosporin	thrombocytopenia, pemphigus, sebaceous adenitis	4 - 6 mg/kg	4hr IV infusion	q 24 hrs (avoid extravasation)
		3 - 7 mg/kg	PO	q 12 hrs
Cyclosporin ophthalmic	keratoconjunctivitis sicca	1 - 2% solution	drop in eye	q 12 hrs
Cyclothiazide	diuretic	0.5 - 1.0 mg/kg	PO	q 24 hrs
Cytarabine	Chemotherapy	30-50 mg/kg	IV, IM, SQ	once a week
		100 mg/m2	IV. IM, SQ	q 24 hrs for 4 days then
		20 mg/m2	Intrathecal	q 24 hrs for 1 - 5 days
Dacarbazine	Lymphoreticular neoplasms	200 - 250 mg/m2	IV	q 24 hrs for 5 days, every 21 days
	Soft tissue sarcomas	1000 mg/m2	IV infusion	over 6 - 8hrs, every 21 days
Dactinomycin	Chemotherapy	0.015 mg/kg	IV	q 24 hrs for 3 - 5 days, wait 3 weeks then
		0.1 - 1.5 mg/m2	IV	weekly
Dalteparin	DIC, Thrombosis	70 IU/kg	SQ	q 24 hrs
Dapsone	Mycobacterium spp	1.1 mg/kg	PO	q 12 hrs for 4 - 6 weeks
Deferoxamine mesylate	Iron chelator	10 mg/kg	IV, IM, SQ	q 2 hrs for 2 doses then q 8 hrs for 24 hrs
	Reperfusion (ischaemia) injuries	50 mg/kg	IV	over 5 mins
Deprenyl	hyperadrenocorticism	1 - 2 mg/kg	PO	q 24 hrs
Desmopressin acetate	diabetes insipidus	0.3 µg/kg	IM	q 12 - 24 hrs
Desoxycorticosterone acetate	hypoadrenocorticism	0.2-0.4 mg/kg	conjunctivally	q 24hrs, max 5mg
Desoxycorticosterone pivalate	hypoadrenocorticism	25 mg	IM	stat
Dexamethasone	central oedema, spinal cord trauma, DJD, other CNS trauma	2 mg/kg	IV	then,
		1 mg/kg	IV, SQ	q 8 - 12 hrs, then
		0.1 mg/kg	IV, SQ, PO	q 8-12hrs
	hydrocephalus	0.25 mg/kg	IV, IM, PO	q 6 - 8 hrs
	shock, anaphylaxis	4 - 6 mg/kg	IV (slowly)
	immune-mediated disease	0.25 - 1.25 mg/kg	PO	q 12 - 24 hrs
		0.1 - 0.15 mg/kg	SQ, PO	q 12 hrs for 5 - 7 days, then taper dose
	hypoadrenocorticism	0.1 - 0.5 mg/kg	SQ, IV	with mineralocorticoids
	asthma	1 mg/kg	IV	then
		0.25 - 1.0 mg/cat	PO	q 8 - 24hrs
Dexrazoxane	iron chelation for doxorubicin-induced cardiotoxicity	25 mg/kg (ratio of 10-20:1 dexrazoxane : doxorubicin)	IV	15 mins before doxorubicin
Dextran 40	Shock	10 - 20 ml/kg	IV	q 24 hrs
Dextran 70	Volume expander	10 - 20 ml/kg	IV	q 24 hrs to effect
Dextromethorphan	coughing	0.5 - 2.0 mg/kg	PO, SQ, IV	q 6 - 8 hrs
Dextrose, 50%	hypoglycemia, insulin overdose	2 ml/kg	PO
		0.25 - 1.0 ml/kg	IV
Dextrose, 5%	hypoglycemia, insulin overdose	40 - 50 ml/kg	IV, SQ, IP	as needed
Diazepam	Pre-med, Behavior modification	0.5 - 2.2 mg/kg	PO	as needed
	seizures	0.15 - 0.70 mg/kg	PO, IV	q 8 hrs
	status epilepticus, toxins	0.5 - 1.0 mg/kg	IV	in increments of 5 - 20 mg
	strychnine-induced seizures	2 - 5 mg/kg	IV	as needed
		0.5 mg/kg	IV
Dichlorphenamide	Glaucoma	3 - 5 mg/kg	PO	q 8- 12 hrs
Dicloxacillin	Susceptible infections	10 - 50 mg/kg	PO	q 6 - 8 hrs
Diethylcarbamazine	heartworm disease	6.6 mg/kg	PO	q 24 hrs
Diethylstilboestrol	incontinence	0.01-0.02 mg/kg	PO	q 24 hrs
Difloxacin	Susceptible infections	5 - 10 mg/kg	PO	q 24 hrs
Digoxin	Congestive heart failure	0.005 - 0.008 mg/kg	PO	q 12 hrs
Dihydrotachysterol	milk fever, hypoparathyroidism	0.03 - 0.06 mg/kg	PO	q 24 hrs for 3, then
		0.01-0.02 mg/kg	PO	q 24hrs
Diltiazem	hypertension, hypertrophic cardiomyopathy, supraventricular tachycardia	0.5 - 2.5 mg/kg	PO	q 8 hrs
Dimenhydrinate	Antihistamine	1.0 - 3.0 mg/kg	PO, IM, IV	as needed
Dimercaprol	Arsenic toxicosis	2.5 -5.0 mg/kg	IM	q 4 hrs for 2 days, then q 8hrs for 3 days, then q 12hrs for 10 days
Dimethylsulfoxide	Spinal cord trauma, amyloidosis	0.5 - 1 g/kg	IV (10%)	q 6 - 8 hrs over 45 min
Diminazine aceturate	Babesia spp, Trypanosoma spp	2.0 - 3.5 mg/kg	IM	Once
		3.5 mg/kg	IM, SQ	q 24 hrs for 2 days
Dinoprost	see prostaglandin F2a
Diphenhydramine	Antihistamine	2 - 4 mg/kg	PO	q 6 - 8 hrs
	mast cell tumour, antiemetic	2 mg/kg	IM, IV	q 12 hrs as needed
Diphenoxylate	ulcerative colitis	0.05 - 0.1 mg/kg	PO	q 12 hrs
Diphenylthiocarbazone	Thallium toxicosis	50 - 70 mg/kg	PO	q 8 hrs
Diphemanil methylsulphate	bronchodilator	1.8 mg/kg	IM	q 12 hrs
Dipyridamole	thromboembolism	4 - 10 mg/kg	PO	q 24 hrs
Disodium EDTA	Calcium keratopathy	0.37% solution	topically	lavage cornea for 15 - 20 mins
Dobutamine	Positive ionotrope	0.5 - 2.0 µg/kg/min	IV infusion (caution)	1 min
Dolasetron	antiemetic	0.6 mg/kg	PO, IV, SQ	q 24 hrs
Dopamine	hypotension, shock, inotropic agent	2 - 25 µg/kg	IV infusion	1 min
Doxapram	Respiratory stimulant in neonates	1 - 5 mg/kg	IV (umbilical vein)	as needed
		1 - 2 drops	PO	as needed
Doxorubicin	chemotherapy	10 - 30 mg/m2	IV	q 21 days
Doxycycline	Susceptible infections	5 - 10 mg/kg	PO, IV	q 12 - 24 hrs
Edrophonium	myasthenia gravis diagnosis	2.5 mg/dog	IV	stat
Emodepside	anthelmintic	1 x vial	topically	monthly
Enalapril	hypertension, congestive heart failure, valvular endocardiosis	0.25 - 0.5 mg/kg	PO	q 12 - 24 hrs
Enilconazole 10%	Aspergillus spp	5% solution (1:1 in water)	topically	q 12 hrs for 7 - 10 days
		10-20 mg/kg (10% solution: 50:50 in water	instil into nasal sinus	q 12hrs for 10 - 14 days
Enrofloxacin	Susceptible infections	5.0 - 20.0 mg/kg	PO, SQ, IM, IV (with caution - may cause blindness)	q 24 hrs for 7 - 10 days
Ephedrine	bronchodilator, incontinence	2.0 - 5.0 mg/kg	PO	q 8 - 12 hrs
Epinephrine	cardiac arrest	0.2 ml/kg	IV, intratracheal	q 5 - 15 min as needed
Epsiprantel	Dipylidium spp, Taenia spp	2.5 - 2.75 mg/kg	PO	stat
Ergocalciferol	Vitamin D	500 - 2000 IU/kg	PO	q 24 hrs
Erythromycin	Susceptible infections	10 - 22 mg/kg	PO, IV	q 8 hrs
Erythropoietin	anemia	50 - 100 IU/kg	SQ	3 x weekly for 12 weeks then twice weekly (as need to maintain PCV at 35%)
		400 IU/kg	IV, SQ	once a week
Esmolol	Selective B1 blockade	0.05 mg/kg	slow IV	loading dose, then
		50 - 200 µg/kg	IV infusion	per min
Estradiol cypionate	mesalliance	125 - 250 µg	IM	between 40hrs and 5 days post-coitus
Ethosuximide	seizures	40 mg/kg	PO	load, then
		20 mg/kg	PO
EDTA	anticoagulant, chelation	1 mg/kg	IV	q 2hrs
Etidronate disodium	hypercalcaemia	10 mg/kg	PO	q 2 hrs
Etomidate	general anesthesia	0.5 - 3.0 mg/kg	IV	as needed
	With opioids	0.5-1.0 mg/kg	IV	as needed
Etretinate	dermatopathy	1 - 2 mg/kg	PO	q 24 hrs
Famotidine	antacid	0.5 mg/kg	IM, SQ, PO	q 12 - 24 hrs
Febantel	anthelmintic	10 mg/kg per 1mg/kg praziquantel	PO	q 24 hrs for 3 days
Fenbendazole	anthelmintic	25 - 50 mg/kg	PO	q 12 hrs for 3-14 days
Fentanyl	analgesia	0.01 mg/kg	IV, SQ, IM
Fitergol	cognitive dysfunction syndrome	1 - 5 mg/dog	PO	q 24hrs
Flavoxate	Incontinence (Detrusor hyperspasticity)	100 - 200 mg/dog	PO	q 6 - 8 hrs
Florfenicol	Susceptible infections	22 - 50 mg/kg	PO, IM, SC	q 12 hrs
Fluconazole	fungal infections	2.5 - 10.0 mg/kg	PO with food	q 12 - 24 hrs
Flucytosine	Cryptococcus spp	30 - 50 mg/kg	PO	q 6 - 8 hrs
Fludrocortisone	hypoadrenocorticism	0.1 - 0.2 mg/dog	PO	q 24 hrs
Flumazenil	hepatic encephalopathy	0.2 mg/dog	IV	as needed
Flumethasone	anti-inflammatory	0.15 - 0.3 mg/kg	IV, IM, SQ	q 24 hrs
Flunixin meglamine	analgesic, anti-pyretic	0.5 - 2.2 mg/kg	IV, IM, SQ	oid for 3 days, then repeat after 4 days
Fluoxetine	Behavioural problems	0.1 - 2.0 mg/kg	PO	q 24 hrs
Flurazepam	seizures	0.2 - 0.4 mg/kg	PO	q 4 - 7 days
Flurbiprofen	Conjunctivitis	0.2 - 0.4 mg/kg	Topically	q 8 - 12 hrs
Folic acid	Dietary supplement	0.5 - 1.0 mg/kg	PO	q 24 hrs
Follicle stimulating hormone (FSH)	Induction of oestrus	500 IU HCG	IV, IM, SQ	q 24 hrs for 5 days
Fomepizole	Ethylene glycol toxicity	20 mg/kg	IV	stat
Furosemide	diuretic	2 - 4 mg/kg	IV, IM, PO	q 8 - 12 hrs as needed
Gabapentin	Epilepsy	10 mg/kg	PO	q 8 - 12 hrs
Gamma globulin	Immune-mediated disease	1 g/cat	IV	q 6 - 12 hrs
Gentamicin	Susceptible infections	6 - 8 mg/kg	IM, SQ, IV	q 24 hrs
Glimipiride	Non-insulin-dependant diabetes mellitus	0.25 - 0.5 mg/kg	PO	q 24 hrs
Glipizide	Non-insulin-dependant diabetes mellitus	0.25 - 0.5 mg/kg	PO	q 8 - 12 hrs
Glycopyrrolate	Bundle branch block	0.005 - 0.010 mg/kg	IV, IM	as needed
Gold sodium thiomalate	Immune-mediated disease	0.25 - 1.0 mg/kg	IM	weekly x 3; 2nd + 3rd week at 2 - 10 mg/cat
Gonadotropin releasing hormone (GnRH)	Ovarian cystadenoma, detection of ovarian remnant syndrome	25 µg/dog	IM	single treatment
Granisetron	Chemotherapy-associated vomiting	0.1 - 0.5 mg/kg	IV, PO	q 12 - 24 hrs
Granulocyte colony stimulating factor	Neutropenia	3 - 10 µg/kg	SQ	q 12 - 24 hrs
Griseofulvin	Antifungal	10 - 30 mg/kg	PO	q 24 hrs for 4 weeks
Guaifenesin	Tranquiliser	44 - 88 mg/kg	IV	stat
Halofuginone	Coccidiostat, Immunosuppressant	100 µg/kg	PO	q 24 hrs
Halothane	General anesthesia	Induction: 3%	Inhalant	stat
		Maintenance: 0.5-1.5%	Inhalant	as needed
Haemoglobin (polymerised bovine)	Blood replacement	10-30 ml/kg	IV	stat
Heparin	Thromboembolism, thrombophlebitis	Initial dose: 100-200 IU/kg	IV	then
		Maintenance dose: 50-100 IU/kg	SQ	q 6 - 8hrs
	Thromboembolism	Induction 1000 IU/kg	IV	then
		Maintenance: 50 IU/kg	SQ	q 8hrs
	Pancreatitis	50-1000 IU/kg	SQ	q 8 - 12hrs
	DIC	75-100 IU/kg	IV, SQ	q 6hrs
	Lipoprotein lipase provocation test	100 IU/kg	IV	test lipids before and 15 mins after heparin
Heparin, LMW	see Dalteparin
Hetacillin	Susceptible infections	10 - 20 mg/kg	PO	q 8 - 12 hrs not associated with feeding
Hetastarch (Hydroxyethyl starch)	Plasma volume expander	10 - 20 ml/kg	IV	as needed
Human gammaglobulin	Immune-mediated disease	0.5 - 1.5 g/kg	IV	q 12 hrs (infusion)
Hydrocodone	Antitussive	0.22 mg/kg	PO	q 12 hrs
Hyaluronate sodium	Synovitis	0.5 - 1.0 mg/kg	intra-articular	q 7 days
Hydralazine	Vasodilator: congestive heart failure	0.5 mg/kg, titrate up to 0.5 - 0.8 mg/kg	PO	q 12 hrs
Hydrochlorothiazide	Hypertension	0.5 - 2.0 mg/kg	PO	q 12 - 24 hrs
	Nephrogenic diabetes insipidus	0.5 - 5.0 mg/kg	PO	q 12 hrs
	Hypoglycaemia	2 - 4 mg/kg	PO	q 12 hrs
	Calcium oxalate uroliths	2 mg/kg	PO	q 12 hrs
Hydrocortisone	Replacement therapy	0.5 - 1.0 mg/kg	PO	q 24 hrs
	Anti-inflammatory	2.5 - 5.0 mg/kg	PO	q 12 hrs
Hydrocortisone aurate	Hypoadrenocorticism	0.1 - 0.2 mg/kg	IM	q 8 - 12 hrs
	Immune-mediated haemolytic anaemia	2 - 4 mg/kg	IM	q 12 - 24 hrs
Hydrocortisone sodium succinate	Shock	8 - 150 mg/kg	IV	stat
Hydrogen peroxide (3%)	Emetic	5-10 ml/cat	PO	stat
Hydromorphone	Analgesia	0.05 - 0.1 mg/kg	IM, SQ	every 24 hrs
Hydroxyurea	Primary polycythemia	25 - 30 mg/kg	PO	q 3 days
	Chronic granulocytic leukaemia	0.5 g/m2	PO	q 12hrs for 4-6 weeks, then halve dosage
Hydroxyzine	Antihistamine	5-10 mg/cat	PO	q 12hrs
Hypertonic saline	Shock	2-6 ml/kg	rapid IV infusion	stat
Idarubicin HCl	Antiviral	2.0 mg/kg	PO	q 24hrs for 2 days, then repeat q21 days
Idoxuridine	Ocular herpes viral infection	0.1% solution: 1 drop	topically	q 4 - 6 hrs
		0.5% ointment	topically	q 1 hr
Imatinib mesylate	Chemotherapy	10 mg/kg	orally	once daily
Imidacloprid	Fleas	100 mg/ml	topically	0.1 cc/kg monthly
Imidocarb	Ehrlichia spp	5 mg/kg	IM	every 14 days x 2
Imidapril	Congestive heart failure and Chronic renal disease	0.5 mg/kg	PO	q 24hrs
Imipenem-cilastin	Susceptible infections	2 - 10 mg/kg	IM or slow IV	q 6 - 8 hrs
Imipramine	Behavioural modification, urinary incontinence	2.5 - 5.0 mg/cat	PO	q 12 hrs
Insulin, glargine	Diabetes mellitus	0.25-5.0 U/kg	SQ	q 12hrs, adjust as needed
Insulin, lente	Diabetes mellitus	0.5 U/kg	SQ	q 12 - 24hrs
Insulin, NHP	Diabetes mellitus	1 - 3 U/dog	SQ	q 12 - 24hrs
Insulin, PZI	Diabetes mellitus	1 - 3 U/dog	SQ	q 12 - 24 hrs
Insulin, regular	Diabetes mellitus	1 - 2 U/dog	SQ	q 6 - 8 hrs
Insulin, ultralente	Diabetes mellitus	1-3 U/dog	SQ	q 12 - 24hrs
Interferon a2, human recombinant	Immunostimulant	15 - 30 U/dog	IM, SQ, PO	q 24 hrs on alternate weeks
Iodine	Hyperthyroidism	50 - 100 mg/dog	PO	q 24 hrs
Iodide sodium, potassium 20% solution	Hyperthyroidism	20 mg/kg	PO	q 12 - 24 hrs
Iopamidol	Myelography	0.25 ml/kg	intrathecal	stat
Ipecac syrup	Emetic	2 - 6 ml/dog	PO	stat
Ipodate	Hyperthyroidism (short term)	15 mg/kg	PO	q 12hrs
Iron dextran	anemia	50 mg	IM	at 18 days of age
Isoflurane	Gaseous anaesthesia	Induction: 5% Maintenance: 1.5-2.5%	Inhalation	stat
Isoniazid	Mycobacterium spp	10 - 20 mg/kg	PO	q 24 hrs
Isopropamide	Bundle branch block	0.2 - 0.4 mg/kg	PO	q 8 - 12 hrs
	Antidiarrhoeal, GIT hypermotility	0.2 - 1.0 mg/kg	PO	q 12 hrs
Isoproterenol	Bundle branch block	0.04 - 0.08 µg/kg	IV infusion	as needed
Isosorbide dinitrate	Vasodilator, osmotic diuretic, megaoesophagus	2.5 - 5.0mg	PO	q 12 hrs
Itraconazole	fungal infections	5 - 10 mg/kg	PO	q 12 - 24 hrs
Ivermectin	Heartworm disease prophylaxis	24 µg/kg	PO	once monthly
Kanamycin	Susceptible infections	10 - 15 mg/kg	IV, IM, SQ	q 12 hrs
	GI tract bacterial overgrowth	10 - 12 mg/kg	PO	q 8 - 12 hrs
Kaolin / pectin	GI tract protectant	1 - 2 ml/kg	PO	q 2 - 6 hrs
Ketamine	general anesthesia	7 - 11 mg/kg	IV, IM	stat
Ketoconazole	fungal infections	5.0 - 10.0 mg/kg	PO	q 12 - 24 hrs
Ketoprofen	analgesic	0.2 - 1.0 mg/kg	PO, IM, SQ	q 24 hrs for less than 5 days
L-asparaginase	chemotherapy	10,000 U/m2	IV	weekly as part of a protocol
Lactated Ringer's solution	Rehydration	40 - 50 ml/kg	IV	q 24 hrs
Lactilol	Stool softener, hepatic encephalopathy	250 ml	PO	q 12 hrs
Lactoferrin	periodontitis	40 mg/kg	Topical	q 24 hrs
Lactulose	megacolon, hepatic encephalopathy	2.5-5.0 ml	PO	q 8 - 12 hrs
Lamasil	fungal infections	20 - 30 mg/kg	PO	q 24 hrs for 4 - 10 weeks
Leucovorin	Methotrexate toxicity	3 mg/m2	IM	within 3 hrs of poisoning
Levallorphan	Opioid toxicity/overdose	0.02 - 0.20 mg/kg	IV	as needed
Levamisole	heartworm disease	10 mg/kg	PO	q 24 hrs for 7 days
Levetiracetam	seizures, cognitive disorder	15 - 20 mg/kg	PO	q 8 - 12 hrs
Levodopa	hepatic encephalopathy	6.8 mg/kg initially, then 1.4mg/kg	PO	q 6 hrs
Thyroxine	Hypothyroidism	10-30 µg/kg	PO	q 12hrs
Lidocaine	Ventricular arrhythmias, epidural	0.25 - 1.0 mg/kg	IV, intrathecal	stat
Lime sulphur	Sarcoptes spp	1:40 dilution	Topically	weekly for 6 weeks
Lime water	Alkaline gastric lavage	5 ml/kg	PO	stat
Lincomycin	Susceptible infections	11 - 33 mg/kg	PO, IV, IM	q 12 - 24 hrs
Lisinopril	congestive heart failure, hypertension	0.25 - 5.0 mg/kg	PO	q 24 hrs
Lobaplatin	chemotherapy	35 mg/m2	IV	q 3 hrs
Lomustine	chemotherapy	100-150 mg/m2	PO	q 6 weeks (subsequent dose based on WBC)
Loperimide	Antidiarrhoeal	0.1 - 0.3 mg/kg	PO	q 12 - 24 hrs
Luteinizing hormone	Stimulate ovulation	50 IU	IM	after mating
Magnesium sulphate (25%)	Hypomagnesemia	5 - 15 mmol	IM, IV	over 1 - 2 hrs
Mannitol 5-20%	oliguric renal failure	0.25 - 1.0 g/kg	IV over 15 - 60 min	q 4 - 6 hrs to maintain urine flow
	Glaucoma	1 - 3 mg/kg	IV over 15 - 20 min
	CNS oedema	1.5 mg/kg	IV	stat
Marbofloxacin	Susceptible infections	2.75 - 5.5 mg/kg	PO	q 24 hrs
Maropitant	Anti-emetic	1.0 mg/kg	SQ/PO	q 24 hrs for 4 days, then rest 2 days
Mebendazole	Parasites	22 mg/kg	PO	q 24 hrs for 3 days
Meclizine	antiemetic	12.5 mg	PO	q 24 hrs, 1 hr before driving
Medetomidine	analgesia, sedative	50-150 µg/kg	IV, IM	stat
Medroxyprogesterone acetate	aggression	1 - 2 mg/kg	IM	once weekly, stop 7-10 days before parturition
Megestrol acetate	estrus suppression	0.5 - 1.0 mg/kg	PO	q 24 hrs for 10 days, then q 48hrs for 5 treatments, then as needed
Meglumine antimonate	Leishmaniasis	5 - 30 ml/dog	IV, IM, IP	q 48 - 72 hrs
Melatonin	Anterior uveitis	0.01 - 1.0 mg	PO	q 24hrs
Meloxicam	analgesia	0.01 - 0.03 mg/kg	PO	q 24 hrs as needed
Melphalan	chemotherapy	0.05 mg/kg	PO	q 24 hrs for 2 weeks, then q 48hrs
Mepivacaine	Local analgesia	1 - 5 ml of 2% solution	SQ	as needed
Mesna	Haemorrhagic cystitis associated with cyclophosphamide	40% of cyclophosphamide dose	PO, IV, IM, SQ	q 3 hrs x 6 at time of cyclophosphamide treatment, follow with repeat dose (24 hr infusion)
Metamucil	Laxative	2-4 g	in moistened food	q 12 - 24 hrs
Metaproterenol	Bronchodilation	0.325 - 0.65 mg/kg	PO	q 4 - 6 hrs
Metaraminol	Vascular support during shock	0.01 - 0.1 mg/kg	IV slowly	stat
Metformin	diabetes mellitus)	2 mg/kg	PO	q 12 hrs
Methazolamide	glaucoma	1 - 2 mg/kg	PO	q 12 hrs
Methicillin	Susceptible infections	20 mg/kg	IM, IV	q 6 hrs
Methocarbamol	Muscle relaxation	20 - 66 mg/kg	PO	q 8 - 12 hrs
Methohexital	Anaesthesia induction	2.5% solution: 11 mg/kg	IV	stat
Methotrexate sodium	Chemotherapy	2.5 mg/m2	PO	q 24hrs or 2 - 3 x weekly, in a protocol on day 14 with 5 mg prednisolone PO q 12hrs
	Carcinomas, sarcomas	10-15 mg/m2	PO	q 1 - 3 weeks
Methoxamine (a1-agonist)	Vasopressor: cardiac arrest, shock	200-250 µg/kg or 40-80 µg/kg	IM	stat
Methoxyflurane	Inhalation anaesthesia	Induction: 3%, Maintenance: 0.5-1.5%	Inhalation	stat
Methscopolamine bromide	Anti-emetic	0.3-1.0 mg/kg	PO	q 8hrs (use cautiously)
Methylcellulose	Laxative	1.0-1.5 g/cat	PO	as needed
Methylene blue 0.1%	Indicator dye	3 mg / 250 ml 0.9% NaCl	IV over 30-40 min
	Antidote	1-1.5 mg/kg	IV	stat
Methylprednisolone	Antiinflammatory	0.5-1.0 mg/kg	PO	q 12hrs
Methylprednisolone acetate	Asthma	1-2 mg/kg	IM	q 7 days
	Others	5.5 mg/kg	SQ, IM	1 - 24 weeks
Methyltestosterone	Anabolic steroid	1 - 2 mg/kg	PO	q 24 hrs
	Testosterone-responsive dermatoses	1-2.5 mg/cat	PO	q 48hrs
Metoclopramide	Gastric motility disorders, antiemetic	0.2 -0.5 mg/kg	PO, IM, SQ	q 8 hrs
		1.0 - 2.0 mg/kg	IV	q 24 hrs
	Gastric reflux	0.2-0.4 mg/kg	PO	q 8hrs, 30 mins before meals
Metoprolol	Atrial fibrillation, hypertrophic cardiomyopathy	0.05 - 3.0 mg/kg	PO	q 8 hrs
Metronidazole	Colitis, Coccidiosis, anaerobic infections	10 - 25 mg/kg	PO	q 24 hrs for 7 - 14 days
	Gingivitis	50 mg/kg	PO	q 24 hrs
Metyrapone	Cushing's syndrome	65 mg/kg	PO	q 12 hrs
Mirtazepine	Antiemetic	0.75 mg/kg	PO	q 3 days
Misoprostol	Mucosal protectant	3 - 5 µg/kg	PO	q 12 hrs as required
Miconazole cream	Fungal infections	1 - 3 cm	topically	q 24 hrs for 2 - 4 weeks
Midazolam	Preanaesthetic, sedation,	0.06 - 0.22 mg/kg	IM, IV	stat
	Control of seizures	0.2-0.5 mg/kg	IV	stat
Milbemax	Heartworm and intestinal worm prophylaxis	0.5 - 2.0 mg/kg	PO	monthly
Silymarin	Free radical scavenger	50 - 250 mg/kg	PO	q 12 hrs
Mineral oil	Laxative	5-10 ml/cat	PO, per rectum	q 12hrs
Mithramycin	Hypercalcaemia, testicular cancer, malignancies	0.25 - 0.50 µg/kg	IV	q 24 hrs x 2
Mitotane (o,p-DDD)	Pituitary-dependant hyperadrenocorticism	25 mg/kg	PO	q 7 days (maintenance)
Mitoxantrone	Anticancer chemotherapy	6.0 - 6.5 mg/m2	IV	q 3 - 4 weeks x 4 - 6
Morphine	Antitussive, analgesia	0.05 - 0.1 mg/kg	SQ, IM	q 4 - 6 hrs
Moxifloxacin	Mycobacterium spp, Bartonella spp]]	5.0 mg/kg	PO	q 24 hours
Naloxone	stereotypic behaviour	20 mg	SQ
	Shock	2 mg/kg	IV	q 1 hr
	Opioid antagonist	0.01 - 0.04 mg/kg	IV	to effect, repeat as needed
Nandrolone	Anaemia	2.0 - 10 mg/kg	IM	weekly
N-acetylcysteine	see Acetylcysteine
Neomycin	Susceptible infections	7 mg/kg	IM, IV, SC	q 24 hrs (nephrotoxic)
	Hepatic encephalopathy	10 - 20 mg/kg	per rectum	q 6 hrs
Neostigmine	Diagnostic aid for myasthenia gravis	20 µg/kg with 0.04 mg/kg of atropine	IV	stat
		2 mg/kg/day	PO	q 24hrs, divided doses
Niacin	Hypertriglyceridemia	50 - 100 mg/day	PO	q 24 hrs
Nitenpyram	Fleas	1 tab	PO	daily as needed
Nitroglycerin 2% ointment	Vasodilator for pre-load reduction	1/8 - 1/4 inch (0.3-0.6cm)	cutaneously	q 6 - 8 hrs
Nitroprusside	Acute Congestive heart failure	0.5-10 µg/kg	IV	q 1 min
Norepinephrine	Positive ionotrope	0.05 - 0.3 µg/kg	IV	q 1 min
Novobiocin	Susceptible infections	10 mg/kg	PO	q 8 hrs
Nystatin	Susceptible infections	100,000 IU	PO	q 8 hrs
Octreotide	Chylothorax, Acromegaly	0.1 mg	SQ	q 8 hrs
Ofloxacin	Susceptible infections	2.5-10.0 mg/kg	PO	q 12hrs
Omeprazole	Gastritis, gastric ulceration	1 mg/kg	PO	q 24 hrs
Ondansetron	Antiemetic	0.5 - 1.0 mg/kg	PO	q 24 hrs
Orbifloxacin	Susceptible infections	2.5 - 7.5 mg/kg	PO	q 24 hrs
Ovarid	(see Megestrol acetate)
Oxymorphone	Preanaesthetic	0.1 - 0.2 mg/kg	IM, IV	with ACP or atropine
Oxytocin	Dystocia	0.5 - 1.0 IU/kg	IV, IM, SQ	q 2 hrs for max of 3 doses
Paclitaxel	Chemotherapy	5 mg/kg	IV	pre-treat for anaphylaxis
Pancuronium bromide	Paralytic agent for controlled anaesthesia	0.044 - 0.11 mg/kg	IV	stat
Parvaquone	Toxoplasmosis	10 - 30 mg/kg	IM	q 24 hrs
D-penicillamine	chronic hepatitis	10 - 15 mg/kg	PO	q 12 hrs
Penicillin G	Susceptible infections	20-30 mg/kg	PO	q 6 - 8hrs
Pentazocine	Analgesia	2.2 - 3.3 mg/kg	IV, IM, SQ	q 4 hrs
Pentobarbital	general anesthesia	25 - 30 mg/kg	IV	to effect
	Status epilepticus	5 - 15 mg/kg	IV	to effect
	Sedation	2 - 4 mg/kg	PO	q 6 hrs
Pentosan polysulfate	Disease modifying agent, arthritis	3 mg/kg	IM, SQ	q 7 days
Pentoxifylline	Dermatomyositis	20 mg/kg	PO	q 8 - 12 hrs
	Autoimmune skin diseases	10 - 15 mg/kg	PO	q 24hrs
Phenamidine isethionate	Babesia spp	7.5 mg/kg	IM, SQ	q 24hrs x 2
Phenobarbital	Status epilepticus	2.5 - 5 mg/kg	PO, IM, IV	q 12 hrs
Phenoxybenzamine	Hypertension, pheochromocytoma	0.5 mg/kg	PO	q 12 hrs
	Detrusor areflexia	0.5 - 2.0 mg/cat	PO	q 8 - 12 hrs
	Relaxation of urinary sphincter	0.5 mg/kg	IV	stat
	Endotoxemia	2.5-10.0 mg/cat	PO	q 24hrs
Phentolamine	hypertension from pheochromocytoma	0.02 - 0.1 mg/kg	IV	stat
Phenylephrine	Vasopressor, decongestant, mydriatic	0.15 mg/kg	IV	as needed
Phenylpropanolamine	incontinence	1.5 - 2.0 mg/kg	PO	q 8 hrs
Phenytoin	Seizures, ventricular arrhythmias	2 - 3 mg/kg	PO	q 24 hrs
Phosphate (K or Na)	Hypophosphatemia	4.5 mg/dl serum phosphate	IV	over 6 hrs
Physostigmine (Syrup)	Myasthenia gravis, Glaucoma, magic-mushroom intoxication	0.25-5.0 mg/cat	IM	q 12hrs
Phytomenadione	See Vitamin K1
Pilocarpine 1% ophthalmic	glaucoma	1 drop	topically	q 6 hrs
Pimaricin	Ocular fungal infections	1 drop	topically	q 3 - 8 hrs
Piroxicam	Analgesia, neoplasia	0.3 mg/kg	PO	q 24 - 72 hrs
Plicamycin	Hypercalcemia, testicular cancer, malignancies	0.25 - 0.50 µg/kg	IV	q 24 hrs x 2
Polyethylene glycol	Lubricant, intestinal cathartic	25 ml/kg	PO	then repeat in 2-4 hrs before GI exam
Polyethylene glycol electrolyte solution	Electrolyte replacement	25 ml/kg	PO	q 2 - 4 hrs
Polymixin B	Sepsis	1 - 2 mg/kg	IV	stat
Posaconazole	Aspergillosis	2.5 - 3.75 mg/kg	PO	q 12 hrs
Potassium chloride	Potassium supplementation	0.10-0.25 ml/kg	PO	q 8hrs
	Hypokalemia	0.5 mEq/kg	IV	not to exceed 0.5 mEq/kg/hr
		1 - 3 mEq	PO. IV	q 24 hrs
		10-40 mEq/500 ml of fluid, depending on serum potassium	IV, SQ	stat
Potassium citrate	Urolithiasis	50-75 mg/kg	PO	q 12hrs
Potassium gluconate	Hypokalemia	5-8 mEq/dog	PO	q 12 - 24 hrs
Potassium iodide	fungal infections	6 - 20 mg/kg	PO	q 24 hrs for 10-14 days
Potassium permanganate (1:2000)	Strychnine toxicosis	5 ml/kg in gastric lavage	PO	stat
Potassium phosphate	see Phosphate
Povidone-iodine	Burns	Apply light coating	Topically	q 12 - 24 hrs
Pradofloxacin	Broad-spectrum antimicrobial	5 - 10 mg/kg	PO, SQ	q 24 hrs for 7 days
Pralidoxime chloride	Organophosphate toxicosis	20 mg/kg	IV, IM, SQ	q 12 hrs
Praziquantel	Dipylidium spp	5 mg/kg	PO	stat
	Paragonimus spp	25 - 30 mg/kg	PO	q 24 hrs for 5-10 days
Prazosin	After load reductions	0.5 - 2.0 mg/dog	PO	q 8 - 12hrs
	Cystitis	0.07 mg/kg	PO	q 8 - 12 hrs
Prednisolone	anti-inflammatory	1 - 2 mg/kg	PO	q 24 hrs (each evening)
	Hypoadrenocorticism	1 mg/kg	PO	q 12 hrs
Prednisolone acetate	Hypoadrenocorticism	0.1-0.2 mg/kg	IM	q 12hrs
Prednisolone sodium phosphate	Shock	15 mg/kg	IV	q 4 - 6hrs
Prednisolone sodium succinate	Allergic bronchitis, asthma	15-30 mg/kg	IV, IM	to effective dose
	Shock	15-30 mg/kg	IV	q 4 - 6hrs
	CNS trauma	15-30 mg/kg	IV	then taper to effective dose
Pregabalin	Epilepsy	5 -10 mg/kg	PO	q 12 hrs
Prilium	Congestive heart failure and Chronic renal disease	150 mg syrup	PO	0.5ml q 24hrs
Procainamide	Ventricular arrhythmias	62.5 mg/dog	PO	q 6hrs
Prochlorperazine	Antiemetic	0.1 mg/kg	IM	q 6 hrs
Promazine hydrochloride	Pre-anaesthetic	2.2 - 6.6 mg/kg	IV	stat
	Antiemetic	1-2 mg/kg	IM, IV	q 4 - 6hrs
Promethazine HCl	Antihistamine, antiemetic	0.2 - 0.4 mg/kg	IV, IM, PO	q 6 - 8 hrs
Propantheline bromide	Acute colitis, ulcerative colitis, antiemetic	0.22 - 0.25 mg/kg	PO	q 8 hrs up to 3 days
	Detrusor hyperspasticity, urge incontinence	0.2 mg/kg	PO	q 6 - 8hrs
Propriomazine	Sedation	1.1-4.4 mg/kg	IV, IM	q 12 - 24hrs
Propofol	General anaesthesia, status epilepticus	Induction: 6 - 8 mg/kg	IV	stat
		Induction: 2.5-4.0 mg/kg	IV	with premedication
		Maintenance: 0.51 mg/kg	IV	q min
Propranolol	Ventricular hypertrophy, aortic stenosis, HCM	0.4 - 1.2 mg/kg	PO	q 8 - 12 hrs
	Ventricular arrhythmias	0.02 - 0.06 mg/kg	IV	over 2-3 min; q 8hrs
		0.25-0.5 mg	IV	followed by
		2.5 - 5.0 mg	PO	q 8hrs
	hypertrophic cardiomyopathy, valvular insufficiency	2.5 mg/cat	PO	q 8 - 12hrs
	Hypertension	2.5 - 5.0 mg/cat	PO	q 8 - 12 hrs
	Tachyarrhythmias from endocrinopathies	2.5-5.0 mg	PO	q 8 - 12hrs
Propylthiouracil (PTU)	Hyperthyroidism	10 mg/kg	PO	q 8 hrs
		10 mg/kg	PO	q 8 - 12 hrs
Prostaglandin F2 alpha	Pyometra, Cystic endometrial hyperplasia	0.10 - 0.25 mg/kg	SQ	q 24 hrs for 3 - 5 days
	Abortion	0.5-1.0 mg/kg; 40 days post-conception	SQ	2 injections 24 hrs apart
Protamine sulphate	Heparin antagonist	1.0-1.5 mg for every 100 IU heparin	IV	stat
Pseudoephedrine	Nasal decongestant	15 - 30 mg/dog	PO	q 8 - 12hrs
	Urinary incontinence	0.2-0.4 mg/kg	PO	q 8 - 12hrs
Psyllium	Bulk laxative	1 - 3 tsp	PO	q 8 - 12 hrs
Pyrantel pamoate	Roundworm, hookworm	10 mg/kg	PO	repeat in 2 weeks
Pyridostigmine bromide	Myasthenia gravis(acquired)	1-5 mg	PO	stat
		0.25 mg/kg	PO	q 24hrs
	Antidote (curariform)	0.15-0.30 mg/kg	IM, IV
	Toxoplasma	0.5-2.0 mg/kg	PO	q 12hrs for 14 - 28days
	Enteroepithelial cycle	2 mg/kg	PO	q 24hrs for 14 - 28 days
Quinacrine	Giardia spp, Coccidiosis	11 mg/kg	PO	q 24 hrs for 5 days
Ranitidine	gastritis, GI tract ulceration	0.5 mg/kg	IV, PO, SQ	q 12 hrs
Retinol	Dermatological lesions	625 - 800 IU/kg	PO	q 24 hrs
Rifampicin	Susceptible infections	10 - 20 mg/kg	PO	q 24hrs
Ringer's solution	Maintenance solution	40 - 50 ml/kg	IV, SC, IP	q 24hrs
Ronidazole (Ronivet)	Tritrichomoniasis	30 mg/kg	PO	q 24 hrs for 14 days
	(warning: low therapeutic margin)	20 mg/kg	PO	q 12 hrs for 14 days
Roxithromycin	Susceptible infections	15 mg/kg	PO	q 24 hrs
Secnidazole	Giardia spp	30 mg/kg	PO	stat
Selegiline	Cognitive disorders	0.5 mg/kg	PO	q 24 hrs
	hyperadrenocorticism	1-2 mg/kg	PO	q 24 hrs
Selamectin	Parasiticide	6 mg/kg	Topical	q 30days
Selenious acid, sodium selenite	Supplementation	0.3 mg/kg	PO	stat
Selenium	Pancreatitis	0.1 mg/kg	IV	stat
Senna	Constipation	5 ml/cat	PO	q 24hrs
Silver nitrate solution (0.5%)	Burns	Saturate wet dressing	Topically	q 12hrs
Sulfadiazine	Burns	Apply light coating	Topically	q 12hrs
Sodium bicarbonate	Renal failure	10-15 mg/kg	PO	q 8hrs
	Toxicoses	50 mg/kg	PO	q 8 - 12hrs
	Hyperkalemic crisis	2-3 mEq	IV	over 30 mins
	Urine alkalisation	0.65-5.85 g	PO	q 24hrs
Sodium chloride	Hypoadrenocorticism	1-5 g	PO	q 24hrs
	Hyponatremia, acute renal failure	1-4 g	PO	q 8hrs
	(0.9% soln)	40-50 ml/kg	IV, SQ, IP	q 24hrs
	Susceptible infections	20 mg/kg	PO	q 24 hrs for 4 - 6 wks
Sodium phosphate	Hypercalcemia	Dilute 1-3 g with water (1:1) and give 10-20 ml	PO	q 8 - 24hrs until stools are soft
Sodium thiopental	Anaesthesia	3-15 mg/kg	IV	to effect
Sorafenib	Chemotherapy	2 mg/kg	PO	once daily
Sorbitol (70% soln)	Stool softener	3 ml/kg	PO	stat
Sotalol	Ventricular arrhythmias	1-2 mg/kg	PO	q 12 hrs
Spectinomycin	Susceptible infections	5-12 mg/kg	IM	q 12hrs
Spiramycin	Toxoplasma spp	12.5 - 23 mg/dog	PO	q 24hrs
Spironolactone	Diuretic: heart failure	2-4 mg/kg	PO
	Hyperaldosteronism	1 mg/kg	PO	q 12hrs
	Hepatic insufficiency	3.0 - 4.0 mg/kg	PO	q 24 hrs
Spironolactone / hydrochlorothiazide	Diuretic, antihypertensive agent	1 - 2 mg/kg	PO	q 12 - 24 hrs
Stanozolol	Anabolic agent, anemia	1 - 2 mg/dog	PO	q 12 hrs
		10 - 25 mg/kg	PO	q 7days
Staphage lysate	Immune stimulant	0.1 - 0.2 ml/cat	SQ	then
		incremental doses to 1.0ml	SQ	1 - 2 for a week, then
		0.5 ml	SQ	weekly for 10 - 12 weeks
Staphylococcal A	Immune stimulant	20 µg/2.75kg	IP	q 3 - 5 days
Streptomycin, dihydro	Leptospirosis, endocarditis, Mycobacterium spp, Yersinia pestis	10 mg/kg	IM	q 6 hrs
Succinylcholine	Paralysis	0.06 - 0.11 mg/kg	IV	stat
Sucralfate	Gastrointestinal ulceration	250-500 mg/cat	PO	q 8 - 12hrs
	Hemorrhagic pancreatitis, vomiting with renal failure	40 mg/kg	PO	q 8 hrs
Sulfadiazine	Nocardiosis	220 mg/kg	PO	for 1 treatment, then
		50-110 mg/kg	PO	q 12 hrs
	Toxoplasmosis	15 - 50 mg/kg (with pyrimethamine)	PO	q 24 hrs, divided, for 14 days
Trimethoprim/Sulphonamides	Susceptible infections	30 mg/kg	PO, SQ	q 24hrs
	Meningitis	15 mg/kg	PO, IV	q 8 - 12 hrs
	Nocardiosis	30 - 60 mg/kg	PO, SQ	q 12 hrs
Sulfadimethoxine	Susceptible infections	25 - 50 mg/kg	PO, IM, IV	q 12 - 24 hrs for max of 21 days
	Coccidiosis	55 mg/kg (loading), then 27.5 mg/kg	PO	q 24hrs
Sulfaguanidine	Coccidiosis	100-200 mg/kg	PO	q 8hrs
Sulfamethazine, sulfamerazine	Coccidiosis	200 mg/kg (loading), then 50 mg/kg	PO	q 12 hrs
Sulfamethoxazole	Susceptible infections	100 mg/kg (loading), then 50 mg/kg	PO	q 12hrs
Sulfamethoxazole/Trimethoprim	Susceptible infections	15 mg/kg	PO	q 12hrs
Sulfasalazine	ulcerative colitis	250 mg/cat	PO	q 8hrs for 3 days, then q 24hrs
	ulcerative colitis	20-25 mg/kg	PO	q 12 -24 hrs
	Susceptible bacterial infections	20 mg/kg	PO	q 12hrs
Sulfisoxazole	cystitis	50 mg/kg	PO	q 8 hrs
Sulfobromophthalein sodium	Hepatic function testing	5 mg/kg	IV	collect serum 30 min after BSP injection
Suprofen ophthalmic	Allergic conjunctivitis	1%	Topically	q 8 - 12 hrs
Tacrolimus	Otitis externa	0.1% lotion	topical	q 12hrs
Telazol	Restraint	6.6 mg/kg	IM	stat
	Anesthesia	11 - 15 mg/kg	IM	stat
Terbinafine	Fungal infections	20 - 30 mg/kg	PO	q 24 hrs for 4 - 10 wks
Terbutaline sulphate	Bronchodilator	0.01 mg/kg	SQ, IM	q 4 hrs
		1.25 - 2.5 mg/cat	PO	q 8 hrs
Testosterone cypionate	Hormone replacement	2.2 mg/kg	IM	q 2 - 3 days
Testosterone, methyl	Anabolic effects	1-2 mg/kg; max 30 mg/day	PO	q 24hrs
Testosterone propionate	Feline symmetrical alopecia	12.5 mg with oestrogen	IM	stat
	incontinence	5 - 10 mg	IM	stat
		0.5 - 1.0 mg/kg	IM	q 2 - 3 days
Tetanus toxoid	Tetanus treatment	0.2 ml (test dose), then give 100-500 units/kg	SQ	watch for anaphylaxis for 30 min
Tetracycline	Acute bronchitis	10 - 25 mg/kg	PO	q 8 - 12 hrs
	Rickettsia spp	15 mg/kg	PO	q 8 hrs for 21 days
	Mycobacterium spp	22 mg/kg	PO	q 8hrs
	Susceptible infections	1 - 5 mg/kg	IV, IM	q 8 - 12 hrs
Theophylline	Bronchodilator	4 mg/kg	PO, IM	q 8 - 12 hrs
Theo-Dur (Sustained release)	Bronchodilator	20 - 25 mg/kg	PO	q 24 hrs, at night
Thiabendazole	Heartworm disease adulticide	35 mg/kg	PO	q 12 hrs for 20 days
	Strongyloides spp	125 mg/kg	PO	q 24 hrs for 3 days
Thiacetarsamide	Heartworm adulticide	2.2 mg/kg	IV	q 12 hrs for 2 days
Thiamine	Thiamine deficiency	1 - 2 mg/dog	IM	q 12 hrs until regression of symptoms
		100 - 250 mg/kg	SQ	q 12 hrs
Thiamylal sodium	Anaesthesia	8.8 - 13.3 mg/kg	IV	after tranquilisation
Thioguanine	Lymphocytic and granulocytic leukaemia	25 mg/m2	PO	q 24hrs for 1-5 days, then 130 days
Thyroid	Hypothyroidism	15 - 20 mg/kg/day	PO	q 24 hrs
Thiopentone	General anaesthesia, status epilepticus	3 - 15 mg/kg	IV	to effect
Thyrotropin	Provocative testing	1 IU/kg	IM	Collect baseline and post-TSH samples
	Acanthosis nigrans, hypothyroidism	1 - 2 IU	SQ	q 24 hrs for 5 days
L-Thyroxine (levothyroxine)	Hypothyroidism	0.5 mg/m2	PO	q 12hrs
		20 - 30 µg/kg	PO	q 24 hrs
Ticarcillin	Susceptible infections	33 - 50 mg/kg	IM, IV	q 6 - 8kg
		55-110 mg/kg	IM, Iv	q 4 - 6hrs
Ticarcillin/clavulanate	As above
Tiletamine / zolazepam	Minor procedure	9.7 - 11.9 mg/kg	IM	stat
	Castration	10.6 - 12.5 mg/kg	IM	do not exceed 72 mg/kg with repeat doses
	Spey	14.3 - 15.8 mg/kg	IM	stat
Tolazoline	Xylazine reversal	2 mg/kg	IV	stat
Tolfenamic acid	Analgesia	4 mg/kg	IM, SQ, PO	q 24 hrs up to 5 days, 3 out of 7 days for long term Rx
Toltrazuril (Baycox)	Coccidiosis	5 - 20 mg/kg	PO	q 24 hrs x 2 - 5 treatments
Toluene	Anthelmintic	267 mg/kg	PO	repeat in 2 - 4 weeks
Tramadol	Opioid analgesia	1 - 2 mg/kg	PO	q 8 - 12 hrs
		12.5 mg/dog	PO	q 12 hrs
Triamcinolone	Gingivitis, pododermatitis, acral lick granuloma	2 - 4 mg	PO	q 24 - 48 hrs
	Pannus, episcleritis	4 mg	Subconjunctival	stat
Triamterene	Diuretic	1 - 2 mg/kg	PO	q 12 hrs
Trientine hydrochloride	Chelating agent	10-15 mg/kg	PO	q 12hrs
Triflupromazine	Behaviour modification	0.1 - 0.3 mg/kg	IM, PO	q 8 - 12 hrs
Triiodothyronine (T3)	Hypothyroidism	4.4 µg/kg	PO	q 8 - 12hrs
Trilostane	Cushing's syndrome	30 mg/kg	PO	q 12 - 24 hrs
Trimethoprim/sulfadiazine	Susceptible infections	15 mg/kg	PO, SQ, IV	q 8 - 12hrs
Tripelennamine	Antihistamine	1 mg/kg	PO, IM	q 12 hrs
Trypan blue	Babesia spp	4 mg/kg	IV	stat
Tylosin	GI bacterial overgrowth	6.6-11 mg/kg	IM	q 12 - 24hrs
	Chronic colitis	25 mg	PO	q 8hrs
Urea	Osmotic	300 mg	IV	stat
Urokinase	thromboembolism	90,000 IU over 20 minutes, then 45,000 IU CRI	IV	for up to 24 hrs
Urofollitropin	Hypogonadotropic anovulation	2 mg/dog	IM	q 24hrs
Ursodeoxycholic acid	chronic hepatitis	5-15 mg/kg	PO	q 24hrs
Valproic acid	Epilepsy	25 - 65 mg/kg	PO	with Phenobarbital
		10-105 mg/kg	PO	alone
Vanadium	Hyperglycaemia	0.2 mg/kg	PO	q 24hrs
Vasopressin, aqueous	Central diabetes insipidus	10 mU/cat	IV, IM	as needed
Vasopressin, tannate in oil	Central diabetes insipidus	2.5-5.0 U/cat	IM	q 1- 7 days
Vecuronium bromide	Paralytic agent for controlled anaesthesia	40 µg/kg	IV	over 30 min
Verapamil	Supraventricular arrhythmias	10 - 15 mg/kg	PO	q 24 hrs, divided
	Conversion of rapid supraventricular tachycardia	1.1-4.4 mg/kg	PO	q 8 - 12hrs
Vinblastine	Mast cell tumour, lymphoma	0.1 - 0.4 mg/kg	IV	q 7 - 14 days
Vincristine	Thrombocytopenia	0.01 - 0.025 mg/kg	IV	q 7 - 10 days
	Lymphosarcoma	0.5-1.0 mg/m2	IV	once weekly
	Neoplasia	0.5 - 0.75 mg/m2	IV	q 7 - 14 days
Viokase	Exocrine pancreatic insufficiency	325 mg	PO	with each meal
Vitamin A	Dietary supplement	400 U/kg	PO	q 24hrs for 10d
Vitamin B1	see Thiamine
Vitamin B2		5-10 mg/cat	PO	q 24hrs
Vitamin B complex	Vitamin B deficiency	0.5-1.0 ml	IV, IM, SQ	q 24hrs
Vitamin C	see Ascorbic acid
Vitamin D	Hypocalcemia	0.02 mg/kg	PO	Initially, then
		0.01 mg/kg	PO	q 24 - 48 hrs
Vitamin D2 (ergocalciferol)	Hypocalcemia	4000 - 6000 U/kg	PO	q 24 hrs, initially, then
		500 - 1000 U/kg	PO	q 24 - 48 hrs
Vitamin D3 (calcitriol - 1-25, dihydroxy vitamin D3)	Hypocalcemia	0.03-0.06 µg/kg	PO	q 24 hrs
	Chronic renal disease	0.025 µg/kg	PO	q 24 hrs
Vitamin E	myopathy, myocarditis, retinal pigment epithelial dystrophy	10 - 20 IU/kg	PO	q 12 hrs
	Pemphigus	400 - 600 IU/dog	PO	q 12 hrs
Vitamin K1	Deficiency, hepatopathy	1 - 3mg/kg	SQ, PO	q 12 hrs for 4 - 6 weeks
		5mg/kg	PO	q 24hrs, divided doses
Warfarin	thromboembolism	0.06 - 0.20 mg/kg	PO	q 24 hrs. Maintain PTT at 2 - 2.5 times normal
Xylazine	Muscle relaxation	1.1 - 2.2mg/kg	IM, SQ	stat
	Emetic	0.44mg/kg	IM
Zafirlukast	Leukotriene receptor antagonist	0.15 - 0.2mg/kg	PO	q 12 - 24 hrs
Zidovudine (AZT)	Antiviral	5 - 20 mg/kg	SQ, PO	q 8 - 12 hrs
Zinc	Antioxidant	2 - 3 mg/kg	PO	q 24 hrs
Zonisamide	Epilepsy	5 mg/kg	PO	q 12 hours