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Thrombopathia is a rare autosomal-recessive genetic form of hemophilia.

This disease is caused by a missense mutation that produces platelets with abnormal fibrinogen receptor exposure and impaired dense granule release, and results in bleeding tendencies primarily of mucosal surfaces.

Thrombopathia has been reported in the Basset Hound[1], Spitz and American Cocker Spaniel[2]


  1. Johnstone IB & Lotz F (1979) An inherited platelet function defect in basset hounds. Can Vet J 20:211–215
  2. Brooks M & Catalfamo J (1993) Buccal mucosa bleeding time is prolonged in canine models of primary hemostatic disorders. Thromb Haemost 70(5):777-780