Difference between revisions of "Uremia"

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There are numerous causes of uremia, including:
 
There are numerous causes of uremia, including:
 
*Dehydration
 
*Dehydration
*Acute [[glomerulonephritis]] - infections, melamine toxicity, [[acetaminophen toxicity]]
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*[[Urolithiaisis]]
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*Acute [[glomerulonephritis]] - infections, toxins such as melamine, [[acetaminophen toxicity}acetaminophen]], [[ethylene glycol]] and various chemotherapy agents (e.g. [[cisplatin]]<ref>Autio K ''et al'' (2007) Microalbuminuria is not associated with cisplatin-induced azotemia in dogs. ''J Vet Intern Med'' '''21(6)''':1198-1202</ref>)
 
*[[Chronic renal disease]]
 
*[[Chronic renal disease]]
 
*[[Nephrotic syndrome]]
 
*[[Nephrotic syndrome]]
 
*Excess dietary consumption of meat
 
*Excess dietary consumption of meat
*Renal hypoperfusion associated with [[congestive heart failure]]
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*Renal hypoperfusion associated with [[congestive heart failure]]<ref>Nicolle AP ''et al'' (2007) Azotemia and glomerular filtration rate in dogs with chronic valvular disease. ''J Vet Intern Med'' '''21(5)''':943-949</ref>
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Clinical signs of uremia are variable due to the large number of causes, but may anorexia, listlessness, vomiting and diarrhea.
  
 
Dogs with renal azotaemia have reduced mean corpuscular volume, packed cell volume and increased mean corpuscular hemoglobin concentration<ref>Buranakarl C ''et al'' (2009) Relationships between oxidative stress markers and red blood cell characteristics in renal azotemic dogs. ''Res Vet Sci'' '''86(2)''':309-313</ref>.
 
Dogs with renal azotaemia have reduced mean corpuscular volume, packed cell volume and increased mean corpuscular hemoglobin concentration<ref>Buranakarl C ''et al'' (2009) Relationships between oxidative stress markers and red blood cell characteristics in renal azotemic dogs. ''Res Vet Sci'' '''86(2)''':309-313</ref>.
  
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Treatment includes Iv fluid therapy and addressing underlying disease cause(s).
  
 
==References==
 
==References==
 
<References/>
 
<References/>

Revision as of 04:16, 15 January 2013

Uremia is defined as an elevated level of blood urea nitrogen above the normal range of 3.1 - 9.2 mmol/L.

There are numerous causes of uremia, including:

Clinical signs of uremia are variable due to the large number of causes, but may anorexia, listlessness, vomiting and diarrhea.

Dogs with renal azotaemia have reduced mean corpuscular volume, packed cell volume and increased mean corpuscular hemoglobin concentration[3].

Treatment includes Iv fluid therapy and addressing underlying disease cause(s).

References

  1. Autio K et al (2007) Microalbuminuria is not associated with cisplatin-induced azotemia in dogs. J Vet Intern Med 21(6):1198-1202
  2. Nicolle AP et al (2007) Azotemia and glomerular filtration rate in dogs with chronic valvular disease. J Vet Intern Med 21(5):943-949
  3. Buranakarl C et al (2009) Relationships between oxidative stress markers and red blood cell characteristics in renal azotemic dogs. Res Vet Sci 86(2):309-313