Named after cases diagnosed in the Aleutian Islands (Alaska), clinical signs of this disease can be nonspecific and acute deaths are common.
Other symptoms include poor reproduction, oral and gastrointestinal bleeding, renal failure and uremia.
Diagnosis can be based on presenting clinical signs, haematological test which reveal hypergammaglobulinaemia, and histopathological changes in the central nervous system and parvovirus-like particles in mesenteric lymph nodes.
A definitive diagnosis requires PCR identification of parvoviral particles in submitted tissues.
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