Imidocarb

From Horse

Imidocarb dipropionate is a urea derivative used as an antiprotozoan drug specifically for treatment of equine piroplasmosis (Babesia spp)[1] and Theileria spp[2].

Side-effects of this drug include colic[3] and diarrhea.

Recommended dose rate in horses is 2.2 mg/kg given intramuscularly. Two treatments are usually administered at a 24-hour interval[4].

For cases of Babesia equi that are resistant to therapy, a dose of 4 mg/kg is administered 4 times at 72-hour intervals.

References

  1. Kutscha J et al (2012) Equine piroplasmosis treatment protocols: specific effect on orocaecal transit time as measured by the lactose 13C-ureide breath test. Equine Vet J Suppl 44(43):62-67
  2. Grause JF et al (2012) Efficacy of imidocarb dipropionate in eliminating Theileria equi from experimentally infected horses. Vet J Nov 28
  3. Donnellan CM et al (2012) Comparison of glycopyrrolate and atropine in ameliorating the adverse effects of imidocarb dipropionate in horses. Equine Vet J Dec 19
  4. Kutscha J et al (2012) Equine piroplasmosis treatment protocols: specific effect on orocaecal transit time as measured by the lactose 13C-ureide breath test. Equine Vet J 44(43):62-67