Lymphoreticular System - Anatomy & Physiology

From Horse

Also referred to as the reticuloendothelial system or mononuclear phagocytic system, the lymphoreticular system of horses is an important immunological arm of the defense system. It is comprised of primary lymphoid organs which are responsible for the production of lymphocytes and the secondary lymphoid organs which function to provide an environment where lymphocytes can react to antigen from the tissue fluid, blood and mucosal surfaces.

The main functions of the lymphoreticular system are removal of senescent cells and production of immune cells.

Primary lymphoid tissues

  • Bone Marrow
  • Thymus
  • Bursa of Fabricius
  • Foetal Liver

Secondary Lymphoid Tissue

  • Lymph Nodes
  • Spleen
  • Mucosal Associated Lymphoid Tissue (MALT)
    • Appendix/caecal pouch
    • Ileal Peyer's Patches
    • Tonsils

Lymphocytes

B Cells

  • B Cell Differentiation and Function
  • Response to Antigen

T Cells

  • T Cell Differentiation and Function
  • Major Histocompatability Complex (MHC) molecule
  • Lymph Nodes
  • Immunoglobulins

Lymphatic Circulation

  • Lymphatic Vessels